Helsinki University Central Hospital

This trial tests whether a 6-month personalized exercise program improves exercise capacity and asthma control in adults with severe asthma who are starting biologic therapy. Participants are randomly assigned to either the exercise program or standard advice to increase physical…

This study compares two common surgical procedures—loop ileostomy and loop colostomy—used as protective stomas after rectal cancer surgery. Researchers want to see which one leads to fewer stoma-related problems within the first 60 days. About 350 patients will be randomly assign…

This study tests whether taking capsules made from healthy donor stool (fecal microbiota transplantation, or FMT) can prevent another bout of C. diff infection in people who have had it come back at least twice. 76 adults will receive either active FMT capsules or placebo, and re…

This study tests whether placing a tiny plastic tube (stent) in the pancreas can lower the chance of pancreatitis after a difficult bile duct procedure called ERCP. About 268 adults who need this procedure will be randomly assigned to get the stent or not. The main goal is to see…

This study looks at whether older adults (80+ or 75+ with health issues) benefit more from gallbladder removal surgery or simply monitoring after their bile duct stones are cleared. About 400 participants will be followed for a year to compare deaths, major complications, and ret…

This study compares two types of mesh surgery for women with pelvic organ prolapse after a hysterectomy. One surgery uses a mesh placed through the vagina, the other uses a mesh placed through small cuts in the belly (laparoscopic). The main goal is to see which surgery works bet…

This study tests whether standard carpal tunnel surgery—cutting a ligament in the wrist—actually relieves symptoms like numbness and pain better than a pretend surgery where the ligament is not cut. About 180 adults with carpal tunnel syndrome will be randomly assigned to real or…

This study tests whether a common back operation (microdiscectomy) actually relieves sciatica leg pain better than a pretend surgery. 122 adults with a herniated disc and persistent leg pain will be randomly assigned to get either the real operation or a sham procedure. Neither t…

This study tests whether dance-movement therapy can reduce depression in teenagers. 140 adolescents with moderate to severe depression will attend 12 group dance therapy sessions. Researchers will measure changes in depressive symptoms using questionnaires and interviews. The goa…

This study compares two ways to manage pain after laparoscopic gallbladder removal. One group gets standard local anesthesia at the incision sites, while the other also receives a nerve block guided by the surgery camera. The goal is to see if the added block reduces pain and the…

This study looks at how chronic pain affects sleep in teenagers aged 15-17. Researchers will test whether listening to a relaxing story before falling asleep can improve sleep quality and help process emotions related to pain. Twenty teens with persistent pain will have their sle…

This study looks at how chronic pain changes the way children and their parents feel emotions in their bodies. Researchers will use emotional body maps to track these sensations. The goal is to better understand the link between pain, emotions, and mood in 600 pediatric patients …