Sham surgery showdown: is carpal tunnel release just a placebo?

NCT ID NCT07614425

Recruiting now Symptom relief Sponsor: Helsinki University Central Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether standard carpal tunnel surgery—cutting a ligament in the wrist—actually relieves symptoms like numbness and pain better than a pretend surgery where the ligament is not cut. About 180 adults with carpal tunnel syndrome will be randomly assigned to real or placebo surgery, and neither they nor their care team will know which they received. The goal is to find out if the surgery itself is effective or if improvement comes from natural healing or the placebo effect.

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARPAL TUNNEL SYNDROME

Contacts and locations

Locations

HUS group, Helsinki Central University Hospital, Meilahti Bridge Hospital
RECRUITING

Helsinki, Finland
Wellbeing Services County of Pirkamaa, Tampere Central University Hospital
NOT_YET_RECRUITING

Tampere, Finland

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