Sham surgery showdown: is carpal tunnel release just a placebo?

NCT ID NCT07614425

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether standard carpal tunnel surgery—cutting a ligament in the wrist—actually relieves symptoms like numbness and pain better than a pretend surgery where the ligament is not cut. About 180 adults with carpal tunnel syndrome will be randomly assigned to real or placebo surgery, and neither they nor their care team will know which they received. The goal is to find out if the surgery itself is effective or if improvement comes from natural healing or the placebo effect.

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • HUS group, Helsinki Central University Hospital, Meilahti Bridge Hospital

    RECRUITING

    Helsinki, Finland

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wellbeing Services County of Pirkamaa, Tampere Central University Hospital

    NOT_YET_RECRUITING

    Tampere, Finland

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••