Helsinki University Central Hospital

This study looks at whether starting automated insulin delivery (AID) early in children aged 7–16 with type 1 diabetes improves blood sugar control, reduces stress for patients and families, and prevents long-term complications compared to standard insulin injections. One hundred…

This phase 3 trial will test whether giving chemotherapy before surgery helps people with resectable left-sided pancreatic cancer live longer compared to surgery alone. About 381 participants will be randomly assigned to either neoadjuvant chemotherapy (FOLFIRINOX or gemcitabine/…

This study looks back at records of 4300 adults who had open-heart surgery to see if calcium levels in the blood are related to how much they bleed. Researchers will calculate average calcium levels during and after surgery and compare them to a standard bleeding scale. The goal …

This Phase 1 trial in 12 healthy volunteers tests whether cannabidiol (CBD) and cobicistat (a drug that boosts other medications) can increase the amount of oral ketamine that reaches the bloodstream. Ketamine is used for treatment-resistant depression but is usually given by IV …