Helsinki University Central Hospital

This study tested a monthly injection of mepolizumab versus placebo in 95 adults with severe asthma, nasal polyps, and sensitivity to aspirin or similar painkillers. The goal was to see if the drug could improve sinus symptoms and shrink nasal polyps better than placebo. The trea…

This study followed 250 children who received milk oral immunotherapy (OIT) to see how well it works over time. Researchers measured how much milk children could drink without reacting, their quality of life, and the cost of treatment. The goal is to understand if OIT is a practi…

This study looked at whether offering families extra help from a pediatrician and social worker after a child's dental surgery under anesthesia can improve follow-up care. 89 children with severe tooth decay participated. The goal was to see if this support leads to fewer missed …

This study looked at 62 adults with chronic sinusitis and a condition called concha bullosa, where a small bone inside the nose is hollow and enlarged. Researchers compared two surgical methods: crushing the bone versus removing part of it. The goal was to see which approach work…

This study looked at how the body processes esketamine (a drug used for depression and pain) when taken with grapefruit juice or cobicistat. Twelve healthy adults received esketamine as a nasal spray or by mouth, and their blood was tested for drug levels over 24 hours. The goal …

This study looked at how two common drugs—carvedilol (for heart conditions) and diclofenac (a painkiller)—affect the liver's ability to process other medications. Twelve healthy adults took a mix of test drugs after receiving either carvedilol, diclofenac, or a placebo. Researche…