Grapefruit juice may change how esketamine works in the body
NCT ID NCT06726382
First seen Mar 11, 2026 · Last updated May 15, 2026 · Updated 13 times
Summary
This study looked at how the body processes esketamine (a drug used for depression and pain) when taken with grapefruit juice or cobicistat. Twelve healthy adults received esketamine as a nasal spray or by mouth, and their blood was tested for drug levels over 24 hours. The goal was to understand how these substances affect esketamine concentration, not to treat any disease.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Department of Clinical Pharmacology
Helsinki, Finland
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