Drug combo safety check: early study completed
NCT ID NCT06717100
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 1 trial studied how deupirfenidone (LYT-100) and nintedanib interact in 24 healthy adults aged 18-65. Participants took both drugs over several weeks to measure drug levels and check for side effects. The goal was to understand potential drug-drug interactions, not to treat any disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
deupirfenidone (LYT-100) and nintedanib
What this could lead to
If successful, this study could help determine safe dosing when combining these two drugs for future treatments.
What could go wrong
This is a very early, small study in healthy volunteers, not patients. Results may not predict real-world effects or safety in people with disease.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Nucleus Network Pty Ltd (Commercial Rd and St Kilda Rd) - VIC
Melbourne, Victoria, 3004, Australia