New trial aims to improve survival for a tough pancreatic cancer

NCT ID NCT07155629

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This phase 3 trial will test whether giving chemotherapy before surgery helps people with resectable left-sided pancreatic cancer live longer compared to surgery alone. About 381 participants will be randomly assigned to either neoadjuvant chemotherapy (FOLFIRINOX or gemcitabine/nab-paclitaxel) followed by surgery, or upfront surgery. The study aims to fill a gap in evidence for this specific tumor location.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mFOLFIRINOX or nab-paclitaxel plus gemcitabine chemotherapy

What this could lead to

If it works, this could show that giving chemotherapy before surgery helps people with left-sided pancreatic cancer live longer.

What could go wrong

This is a phase 3 trial, but results are not yet available. Chemotherapy has side effects, and it may not improve survival compared to surgery alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Helsinki University Central Hospital

    Helsinki, 00290, Finland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Oulu University Hospital

    Oulu, 90220, Finland

    Contact Phone: •••-•••-•••• Email: •••••@•••••