New hope for Hard-to-Treat pancreatic cancer: experimental combo aims to shrink tumors before surgery

NCT ID NCT07488884

First seen Apr 05, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This early-phase trial tests a new mix of drugs (nogapendekin alfa inbakicept, sotevtamab, zabadinostat, plus standard chemo) in 30 people with pancreatic cancer that is either borderline resectable or locally advanced. The goal is to see if the combination is safe and can shrink tumors enough to allow successful surgery, followed by more immunotherapy. The study focuses on side effects and early signs of effectiveness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PANCREATIC CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

Explore the condition pages connected to this study.