Hackensack Meridian Health

This early-phase study is testing whether giving the antibiotic ceftriaxone in pulses (once every five days for about six weeks) can help people with persistent symptoms after Lyme disease treatment. Twenty participants will be randomly assigned to receive either the antibiotic o…

This study is testing if a simple blood test can help doctors better treat advanced non-small cell lung cancer. The test looks for tiny bits of tumor DNA in the blood. Researchers want to see if this test can tell which patients will do well with immunotherapy alone and which mig…

This study is testing whether giving a targeted radiation drug called Lu-177-PSMA-617 (Pluvicto) before surgery can shrink or eliminate high-risk prostate cancer. Men with a specific type of high-risk prostate cancer that shows up on a special PSMA scan will receive two doses of …

This study is testing if a cardiac rehabilitation program can help people recover better after a stroke. Researchers will enroll 150 stroke survivors to see if adding this supervised exercise and education program to their usual care improves their ability to walk, perform daily …

This study is testing whether injections made from mistletoe extract can help prevent bone cancer from coming back after surgery. It involves 32 young patients (ages 8-30) whose osteosarcoma has returned in their lungs but was completely removed by surgery. Participants receive r…

This study is testing a special support program for people with a common type of heart failure who are leaving the hospital. The program provides education, a self-care kit, and follow-up phone calls to help patients manage their condition at home. The main goal is to see if this…

This study is testing a new three-drug combination (carfilzomib, iberdomide, and dexamethasone, called KID) for people newly diagnosed with multiple myeloma who are eligible for a stem cell transplant. The trial aims to find the safest dose and see how well this combination works…

This early-phase study is testing the safety of a new drug combination used to collect a patient's own stem cells for a transplant. The goal is to find the highest safe dose of the drug carfilzomib when used with other standard medications for this collection process. The study w…

This study is testing whether a specific combination of chemotherapy drugs and radiation given before a stem cell transplant can improve one-year survival for adults with blood cancers. The approach aims to better prepare the body for the transplant while reducing serious complic…

This study is testing whether a special type of PET scan can accurately find prostate cancer that comes back after a patient has received targeted, non-surgical treatment. Researchers will enroll 70 men who have had this type of treatment. They will compare the scan results to a …

This study aims to see if a simple, bedside lung ultrasound scan can predict which late preterm babies will develop serious breathing problems in their first two days of life. Researchers will enroll 300 babies born between 34 and 37 weeks who are initially breathing on their own…

This study is testing a new, non-invasive pad device to see if it can collect enough cells from the uterus to help detect cancer or pre-cancer. Participants will wear the pad for a few hours and then answer questions about how comfortable and easy it was compared to standard test…

This study is testing whether giving men a medication called Flomax (tamsulosin) before chest surgery can prevent a common complication where patients can't urinate afterward. Researchers are enrolling 127 men aged 50+ who are scheduled for chest surgery. The medication, which re…

This pilot study aims to see if using emergency department visits can help more people get screened for lung cancer. It will test a program that identifies eligible patients and provides education to address common barriers like mistrust or lack of knowledge. The goal is to incre…

This study is testing if taking the medication Tamsulosin (Flomax) for a week before chest cancer surgery can help older men avoid a common and uncomfortable problem called post-operative urinary retention (POUR). POUR makes it hard to urinate after surgery, leading to infections…

This study is testing whether placing a special graft made from donated umbilical cord tissue during robotic prostate cancer surgery helps men regain bladder control and sexual function more quickly. It will involve 100 men who are scheduled for a specific type of nerve-sparing s…

This study aims to find the best dose of the pain medication ketorolac for adults coming to the emergency room with severe kidney stone pain. Researchers will compare how well a 15mg dose works versus the standard 30mg dose to relieve pain over two hours. The goal is to provide e…

This study is testing a new online program designed to help people with lung cancer manage stress and anxiety while they wait for the results of their routine scans. The program teaches stress management skills and provides support through a website. Researchers will first test t…

This study aims to find the most effective talk therapy for mothers experiencing postpartum depression (PPD) while their newborn is in the Neonatal Intensive Care Unit (NICU). It will compare two established therapies—Cognitive Behavioral Therapy (CBT) and Interpersonal Therapy (…