Hackensack Meridian Health
Clinical trials sponsored by Hackensack Meridian Health, explained in plain language.
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New drug cocktail may boost stem cell transplant success in blood cancer
Disease control CompletedThis study tested whether adding the drug bortezomib to the standard chemotherapy before a donor stem cell transplant could help people with multiple myeloma live longer without their cancer getting worse. Fifty-four adults received the new drug combo. The main goal was to see if…
Phase: PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Could a new drug combo boost transplant success in lymphoma?
Disease control CompletedThis study tested adding lenalidomide (Revlimid) to standard chemotherapy (RICE) for people with relapsed diffuse large B-cell lymphoma. The goal was to see if the combination is safe and can improve response rates, helping more patients qualify for a stem cell transplant. Only 1…
Phase: PHASE1, PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New cocktail aims to tackle tough myeloma cases
Disease control CompletedThis study tested a combination of thalidomide, bortezomib, and high-dose melphalan followed by a stem cell transplant in 29 patients with advanced multiple myeloma who had already failed one round of treatment. The goal was to find the safest dose of thalidomide and see how well…
Phase: PHASE1, PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Can a drug combo overcome resistance in multiple myeloma?
Disease control CompletedThis study tested whether adding a drug called vorinostat to the standard combination of lenalidomide and dexamethasone could help patients whose multiple myeloma had stopped responding to lenalidomide. The trial enrolled 25 adults with relapsed or refractory multiple myeloma. Th…
Phase: PHASE1, PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Cancer drug shows promise in rare blood cancer
Disease control CompletedThis study tested the drug carfilzomib in 7 people with Waldenström's macroglobulinemia, a rare blood cancer, that had returned after previous treatment. The goal was to see if the drug could shrink tumors and control the cancer. Carfilzomib works by blocking a protein that helps…
Phase: PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New cocktail aims to wipe out CLL early
Disease control CompletedThis phase 2 trial tested a combination of chemotherapy (FCR) plus the drug lenalidomide in 21 people with previously untreated chronic lymphocytic leukemia (CLL). The goal was to see if adding lenalidomide could help more patients achieve a complete response, meaning no signs of…
Phase: PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Could a stem cell 'Education' help tame type 1 diabetes?
Disease control CompletedThis early study tested a new approach called Stem Cell Educator therapy in 13 adults with type 1 diabetes. The treatment involves taking a patient's own blood cells, processing them with stem cells, and returning them to the body. The main goal was to see if it is safe and feasi…
Phase: PHASE1 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Double-Dose transplant strategy shows promise for myeloma patients
Disease control CompletedThis study tested a two-step (tandem) stem cell transplant in 148 people with multiple myeloma. Patients received high-dose melphalan chemotherapy, followed by a second transplant with melphalan plus bortezomib (Velcade). The goal was to see if this approach could delay cancer pr…
Phase: PHASE3 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 26, 2026 18:29 UTC
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Could a simple pad replace invasive biopsies for uterine cancer?
Diagnosis CompletedThis study tested a special pad (PadKit™) worn for 4-6 hours to collect cells shed from the uterus. Researchers wanted to see if the pad could gather enough cells to tell the difference between normal tissue, precancerous changes, and cancer. 80 women scheduled for surgery (some …
Phase: NA • Sponsor: Hackensack Meridian Health • Aim: Diagnosis
Last updated Jun 27, 2026 12:32 UTC
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Your voice may reveal Alzheimer's: new app tested for diagnosis
Diagnosis CompletedThis study tested a smartphone app that analyzes voice recordings to see if it can accurately diagnose mild cognitive impairment (MCI) and Alzheimer's disease. Researchers compared the app's diagnosis to a doctor's diagnosis in 150 adults aged 50 and older. The goal was to see if…
Phase: NA • Sponsor: Hackensack Meridian Health • Aim: Diagnosis
Last updated Jun 27, 2026 08:10 UTC
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Gut bacteria linked to chemo success in aggressive breast cancer
Knowledge-focused CompletedThis study looked at whether the types of bacteria in the gut and inside tumors affect how well chemotherapy works in triple negative breast cancer. Researchers followed 49 patients receiving standard chemotherapy before surgery. They collected samples to see if certain bacteria …
Sponsor: Hackensack Meridian Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Helping with housing and food may get more people screened for lung cancer
Knowledge-focused CompletedThis study tested whether helping people with social needs like housing, food, or transportation could increase lung cancer screening rates. 101 adults aged 50-80 who smoked heavily were split into two groups: one got standard education about lung screening, and the other also go…
Phase: NA • Sponsor: Hackensack Meridian Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Can facebook ads help detect lung cancer earlier?
Knowledge-focused CompletedThis study tested whether Facebook ads and a personalized online tool called LungTalk could increase awareness and knowledge about lung cancer screening among people at high risk. Over 500 participants with a history of heavy smoking were recruited through Facebook. The goal was …
Phase: NA • Sponsor: Hackensack Meridian Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC