Lower dose of common painkiller may work just as well for kidney stone pain

NCT ID NCT05776953

Completed Symptom relief Sponsor: Hackensack Meridian Health Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study tests whether a 15mg dose of the painkiller ketorolac works as well as a 30mg dose for relieving kidney stone pain in the emergency department. About 86 adults with severe pain will receive one of the two doses, and their pain levels will be tracked over several hours. The goal is to see if a lower dose can provide similar pain relief, which could mean fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ketorolac (a nonsteroidal anti-inflammatory drug for pain)
What this could lead to: If successful, this could show that a lower dose of ketorolac provides similar pain relief duration, potentially reducing side effects.
What could go wrong: This is a small, single-center Phase 4 trial with only 86 participants, so results may not apply broadly. The study focuses on short-term pain relief, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agnosia Emergencies Flank Pain pain agnosia Renal Colic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANALGESIA EMERGENCIES FLANK PAIN RENAL COLIC

Contacts and locations

Locations

Hackensack Univarsity medical Center

Hackensack, New Jersey, 07601, United States

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