Hackensack Meridian Health

This study tests a mistletoe extract (Iscador P) in 32 patients whose osteosarcoma has returned in the lungs and has been surgically removed. The goal is to see if the treatment can delay or prevent the cancer from coming back. Participants receive injections of the extract and a…

This Phase 2 trial is testing whether a single dose of Lu-177-PSMA-617 (Pluvicto), a radioactive drug that targets prostate cancer cells, can shrink or eliminate high-risk prostate tumors before surgery. About 54 men with aggressive prostate cancer (Gleason score 8 or higher) wil…

This phase 2 trial is testing a new combination of chemotherapy, radiation, and immune-suppressing drugs for people aged 18-65 with blood cancers who need a stem cell transplant. The goal is to see if this regimen improves survival one year after transplant. About 209 participant…

This phase 2 trial tests whether a blood test that tracks tumor DNA can guide treatment for people with advanced non-small cell lung cancer. Participants will receive either immunotherapy alone or immunotherapy plus chemotherapy, based on their blood test results. The goal is to …

This early-phase study tests a combination of drugs (carfilzomib, cyclophosphamide, dexamethasone, and G-CSF) to see if it can safely and effectively collect stem cells for transplant in people with multiple myeloma. The goal is to find the best dose of carfilzomib that causes th…

This study tests a combination of three drugs—carfilzomib, iberdomide, and dexamethasone—in people newly diagnosed with multiple myeloma who are eligible for a stem cell transplant. The goal is to see if this mix is safe and effective at shrinking the cancer before transplant. Ab…

This study tests a multidisciplinary clinic that provides heart failure patients with educational videos, a self-management kit, and follow-up phone calls after hospital discharge. The goal is to reduce 30-day readmission rates and improve patient satisfaction. The trial enrolls …

This study tests whether taking Tamsulosin (Flomax) for a week before surgery can help older men urinate normally after thoracic cancer surgery. About 46 men aged 55 and older will take the drug and have their bladder checked after surgery. The goal is to see if fewer men need ca…

This study looks at whether a cardiac rehabilitation program can improve recovery for people who have had a stroke. Researchers will enroll 150 stroke survivors and add cardiac rehab to their usual care. They will measure walking ability, daily function, and whether the program r…

This study is testing whether a PSMA-PET scan using a radioactive tracer called 18F-rhPSMA-7.3 can accurately detect prostate cancer that has come back after focal gland treatment. About 70 men who had focal therapy for intermediate-risk prostate cancer will receive the scan, and…

This study tests whether taking Flomax (tamsulosin) before and after chest surgery can prevent urinary retention in men aged 50 and older. Urinary retention is a common complication that can require a catheter and cause discomfort. The trial will compare two dosing schedules—star…

This study compares two remote training programs for 300 people who have had a mild traumatic brain injury (concussion) and struggle with emotional awareness and regulation. One program teaches participants to recognize and label their emotions, while the other focuses on general…

This study tests whether a 15mg dose of the painkiller ketorolac works as well as a 30mg dose for relieving kidney stone pain in the emergency department. About 86 adults with severe pain will receive one of the two doses, and their pain levels will be tracked over several hours.…

This study is testing a stress management program designed for people with lung cancer who are waiting for routine scan results. The program includes a short orientation, self-guided web modules with stress management exercises, and coaching calls. Researchers want to see if the …

This study tests two types of talk therapy—cognitive behavioral therapy (CBT) and interpersonal therapy (IPT)—for postpartum depression in mothers whose babies are in the NICU. About 72 mothers will receive either 4 weeks of one therapy or 8 weeks of both, to see which approach r…

This study looks at whether two different training programs can improve emotional health in people who have had a moderate to severe traumatic brain injury. About 48 adults will take part in 8 one-on-one sessions over a month, learning either to recognize emotions or adopt health…

This study creates a worldwide registry for children diagnosed with Embryonal Tumor with Multilayer Rosettes (ETMR), a rare and aggressive brain tumor. Researchers will collect medical records, tumor tissue, and treatment outcomes from up to 100 patients of any age. The goal is t…

This study is building a registry of 10,000 adults at increased risk for cancer. Participants fill out questionnaires and may provide genetic samples. The goal is to learn more about cancer risk factors and improve screening, not to test a new treatment.

This study looks at whether a lung ultrasound done shortly after birth can predict which late preterm babies (born 34–36 weeks) will have breathing problems in the first two days of life. Researchers will compare three different ultrasound scoring methods. The goal is to help doc…

This study tests a new way to increase lung cancer screening in people at high risk. Researchers will use the emergency department to identify eligible patients and offer them extra help to get a low-dose CT scan. The goal is to see if this approach works better than standard car…