Can a special PET scan spot returning prostate cancer after targeted therapy?
NCT ID NCT07011342
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study is testing whether a PSMA-PET scan using a radioactive tracer called 18F-rhPSMA-7.3 can accurately detect prostate cancer that has come back after focal gland treatment. About 70 men who had focal therapy for intermediate-risk prostate cancer will receive the scan, and the results will be compared to standard biopsy findings one year after treatment. The goal is to see if this imaging method can reliably identify recurrence without relying solely on biopsies.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- 18F-rhPSMA-7.3 (a radioactive tracer used in PET scans)
- What this could lead to
- If successful, this scan could become a reliable way to detect prostate cancer recurrence after focal therapy, potentially reducing the need for invasive biopsies.
- What could go wrong
- This is an early-stage study with only 70 participants, so results may not apply to all patients. The scan may miss some recurrences or show false positives.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
John Theurer Cancer Center at Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
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