Gustave Roussy, Cancer Campus, Grand Paris

This study tested a treatment called DA-EPOCH-Rituximab in 47 children and teens with a rare type of lymphoma (PMLBL). The goal was to see if this combination of chemotherapy and a targeted antibody could keep the cancer from coming back. The trial measured how long patients live…

This early-phase study tested a combination of two drugs, temsirolimus and cetuximab, in 45 adults with advanced or metastatic solid tumors that had stopped responding to standard treatments. The goal was to see if blocking two cancer growth pathways at once could be more effecti…

This study tested a chemotherapy drug called cabazitaxel in 34 men with advanced testicular cancer that had not improved after at least two prior treatments. The goal was to see if the drug could shrink tumors or slow the disease. Cabazitaxel is a newer type of taxane that may wo…

This study tested whether adding two targeted drugs (trametinib and dabrafenib) to radioactive iodine can help shrink or control advanced thyroid cancer that has stopped responding to standard radioactive iodine treatment. The trial enrolled 40 adults with specific gene mutations…

This early-phase trial tested a combination of two drugs—pembrolizumab (an immunotherapy) and nintedanib (an anti-angiogenesis drug)—in 196 adults with advanced solid tumors that had worsened after standard treatment. The main goal was to find the safest dose of nintedanib when g…

This study looked at 150 people with colorectal cancer who had a high chance of the cancer spreading inside their abdomen. After standard chemotherapy, half were watched closely, while the other half had surgery to look inside the belly and received heated chemotherapy directly i…

This study tested whether adding the immunotherapy drug atezolizumab to standard chemoradiotherapy helps people with locally advanced cervical cancer live longer without their disease getting worse. About 189 participants received either the standard treatment alone or with atezo…

This study tested whether adding 6 doses of rituximab (a targeted antibody) to standard chemotherapy improves outcomes for 482 children and teens with advanced B-cell non-Hodgkin lymphoma or B-cell leukemia. Participants were aged 6 months to 18 years with high-risk disease. The …

This early-phase study tested the drug RAD001 (everolimus) combined with radiation therapy in 26 people with advanced non-small cell lung cancer that could not be removed by surgery. The main goal was to find safe doses and check side effects. Participants took RAD001 weekly or d…

This study tested a new, optimized version of angiomammography (a special breast X-ray) against the standard method. About 100 women aged 40 to 70 who needed this exam took part. The goal was to see if the new technique produces clearer images with fewer artifacts, which could he…

This study tested whether a personalized telephone-based health education program focused on diet and exercise could reduce fatigue in overweight or obese breast cancer patients. 220 participants were enrolled after completing active treatment. The program used motivational coach…

This study asked men with advanced prostate cancer which of two standard chemotherapies they preferred based on side effects and overall experience. Each patient tried both treatments in sequence and then stated their preference. The goal is to help doctors choose the best first-…

This study tested two improvements for moving cancer patients in wheelchairs inside the hospital: a system to attach IV poles directly to the wheelchair and a more comfortable seat. Researchers measured how these changes affected travel time and patient comfort. 154 adult patient…

This study tested an online program to help cancer patients with insomnia. The program uses a step-by-step approach based on cognitive-behavioral therapy. Researchers wanted to find out which patients need extra help from a professional and what kind of support works best. The st…

This study looked at skin problems caused by newer targeted cancer treatments. Researchers followed 141 cancer patients starting these therapies, tracking any skin reactions through exams and photos. The goal was to learn more about why these side effects happen and how to manage…

This study followed 100 adults with peripheral primitive fibromatosis, a rare non-cancerous tumor, to see how long the disease stays stable without treatment. Participants were monitored with regular check-ups and MRIs, and only received treatment if the tumor grew. The goal was …

This study looked at tumors from 791 children and teens whose cancers had returned or did not respond to standard treatments. Researchers used advanced genetic testing to find specific changes in each tumor that could be targeted by existing drugs. The goal was to see if this per…

This study looked at whether a newer surgical robot, the da Vinci Xi, can be used to remove head and neck tumors through the mouth. 100 adults with various types of head and neck cancer were enrolled. The main goal was to see how often the surgery could be completed successfully …

This study looked at 92 adults who had chemotherapy for bone tumors (osteosarcoma or Ewing sarcoma) as children or teens. Researchers measured their thinking skills and memory using a questionnaire called FactCOG. The goal was to understand long-term brain side effects and what f…