New combo therapy shows promise for hard-to-treat thyroid cancer
NCT ID NCT03244956
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether combining targeted drugs (trametinib and dabrafenib) with radioactive iodine can help shrink or control advanced thyroid cancer that has stopped responding to standard radioactive iodine treatment. The trial enrolled 40 adults with specific gene mutations (RAS or BRAFV600E). The goal was to see how many patients had their tumors shrink significantly or disappear completely.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for METASTATIC RADIOACTIVE IODINE REFRACTORY THYROID CANCER PATIENTS WITH RAS OR BRAF MUTATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Gustave Roussy
Villejuif, Val de Marne, 94805, France