Gilead Sciences

This study is testing a drug called sacituzumab govitecan, both by itself and combined with other treatments, for people with advanced bladder cancer that has spread and cannot be removed by surgery. The main goals are to see if the treatment shrinks tumors and is safe for patien…

This is a first-in-human study to test the safety and find the right dose of a new immunotherapy drug called denikitug. It is being tested alone and in combination with another immunotherapy drug in adults with advanced solid tumors that have stopped responding to available treat…

This study is testing whether an experimental drug called tilpisertib fosmecarbil (GS-5290) can help control symptoms of moderate to severe ulcerative colitis. About 176 adults who haven't responded well to other treatments will receive either the drug or a placebo for 12 weeks. …

This study is testing a new drug called GS-4321 for people with chronic hepatitis delta, a serious liver infection. First, researchers will check the drug's safety and how it moves through the body in healthy volunteers. Then, they will give it to people with the disease to see i…

This is an early-stage study to check the safety and initial antiviral effect of a new HIV medication called GS-3242. It will involve about 30 adults living with HIV who are not currently on treatment. Researchers will measure how the drug affects the amount of virus in the blood…

This early-stage study aims to test the safety and side effects of a new drug called GS-0151 in adults with rheumatoid arthritis. Researchers will give different doses to 75 participants to see how their bodies handle the medication and monitor for any problems. The study will al…

This study is testing a different dose and schedule for the drug sacituzumab govitecan in people with advanced triple-negative breast cancer. The main goals are to see if this new schedule is safe and if it helps shrink tumors or delay cancer growth. The study will enroll about 1…

This is an early-stage study to test a new oral drug called GS-4571 for weight management. Researchers will give the drug to healthy people, people with obesity, and people with type 2 diabetes to see how their bodies process it and to check for side effects. The main goal is to …

This study is testing a long-acting HIV medicine called lenacapavir in children and teenagers who have been treated before and whose current medicines are not fully working. Researchers want to see if the drug is safe, how it behaves in the body, and if it helps control the virus…

This study aims to find better treatment combinations for people with non-small cell lung cancer. It will test several new drug combinations against current standard treatments in three different groups of patients: those newly diagnosed with advanced cancer, those whose cancer h…

This study is testing whether a new two-drug combination given after surgery works better and is safer than standard treatments for people with triple-negative breast cancer that didn't fully disappear with initial therapy. It will involve about 1,500 participants who still have …

This study is testing a new combination of two HIV drugs, bictegravir and lenacapavir, in children and teenagers whose HIV is already well-controlled. The main goals are to find the right dose for young people, see how the drugs move through their bodies, and check for side effec…

This study is testing whether a drug called seladelpar can help prevent serious liver problems in people with primary biliary cholangitis (PBC) who have early-stage scarring (cirrhosis). About 318 participants will be randomly assigned to receive either the study drug or a placeb…

This study aims to test the safety and effectiveness of a medication called tenofovir alafenamide (TAF) for children and teenagers with chronic hepatitis B. It will enroll 150 participants aged 2 to 18 years old. The main goal is to see if TAF can lower the amount of virus in the…

This study is testing whether a newer drug, sacituzumab govitecan, works better than the current standard treatments for people with extensive stage small cell lung cancer that has worsened after their first round of chemotherapy. About 695 participants will be randomly assigned …

This study provides continued access to HIV medications for children and adolescents who have successfully completed an earlier Gilead HIV treatment trial. Its main purpose is to allow these young participants to keep receiving their effective treatment while researchers monitor …

This program provides access to the medication bulevirtide for people with chronic hepatitis D virus infection who have compensated liver cirrhosis. It aims to control the viral infection and reduce liver damage in eligible patients who meet specific health criteria. The treatmen…

This is the first study in people to test a new drug called GS-5319. The main goal is to find a safe dose and understand the side effects in adults with advanced solid tumors that have stopped responding to standard treatments. The drug is designed to work specifically in tumors …

This early-stage study aims to find a safe starting dose of the cancer drug sacituzumab govitecan for people with advanced solid tumors who also have moderate liver problems. Researchers will enroll 30 participants to carefully monitor how the drug behaves in their bodies and wha…

This study is testing a new yearly injection called lenacapavir to prevent HIV infection in people at risk. It will enroll 350 participants to see if the shot is safe and how the drug behaves in the body over a year. The goal is to offer a convenient, long-acting alternative to d…

This study aims to find a safe dose of a three-drug combination pill (B/F/TAF) to prevent HIV infection in newborns whose mothers have HIV. It will enroll 16 full-term, uninfected newborns to check for side effects and measure how the drug moves through their bodies. The goal is …