New Long-Acting HIV shot shows promise for kids and teens

NCT ID NCT06749054

Recruiting now Disease control Sponsor: Gilead Sciences Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a long-acting HIV medicine called lenacapavir (Sunlenca®) in 12 adolescents and children with HIV who have tried other treatments. Participants take lenacapavir as pills and injections along with their other HIV drugs. The goal is to see if the combination is safe, tolerable, and effective at controlling the virus.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lenacapavir (Sunlenca®) given as pills and injections, plus an optimized background regimen of other HIV medicines
What this could lead to: If it works, this could provide a long-acting, easier-to-take option for children and teens with HIV who have limited treatment choices.
What could go wrong: This is a small, early-phase study with only 12 participants, so results may not apply to everyone. Side effects or lack of effectiveness are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV-1-INFECTION

Contacts and locations

Locations

Be Part Research Pty (Ltd)
RECRUITING

Paarl, 7626, South Africa
CRISMO Research Centre
RECRUITING

Germiston, 1401, South Africa
Clinical Research Institute of South Africa (CRISA)
RECRUITING

KwaDukuza, 4449, South Africa
Durban International Clinical Research Site, Enhancing Care Foundation
RECRUITING

KwaZulu - Natal, 4093, South Africa
FAMCRU
RECRUITING

Cape Town, 7505, South Africa
Grady Health System, Ponce De Leon Center
RECRUITING

Atlanta, Georgia, 30308, United States
Perinatal HIV Research Unit (PHRU)
WITHDRAWN

Soweto, 2013, South Africa
Rahima Moosa Mother and Child Hospital
RECRUITING

Johannesburg, 2112, South Africa
Wits RHI Shandukani Research Centre CRS
RECRUITING

Johannesburg, 2038, South Africa

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