New drug targets rare gene fault in advanced cancers
NCT ID NCT07128303
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a new drug called GS-5319 in adults with advanced solid tumors that lack a specific gene (MTAP). The main goals are to check the drug's safety, find the best dose, and see how the body processes it. About 178 people whose cancer has not responded to standard treatments will take part.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Asan Medical Center
RECRUITINGSeoul, 05505, South Korea
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
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NEXT Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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START - Centro Oncológico Clara Campal
RECRUITINGMadrid, 28050, Spain
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START Madrid - FJD - Hospital Fundación Jiménez Díaz - Phase I Clinical Trials Unit
RECRUITINGMadrid, 28040, Spain
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START San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
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Samsung Medical Center
RECRUITINGSeoul, 06351, South Korea
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Seoul National University Hospital
RECRUITINGSeoul, 03080, South Korea
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Vall d'Hebron Institute of Oncology (VHIO)
RECRUITINGBarcelona, 08035, Spain
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Yonsei University Severance Hospital
RECRUITINGSeoul, '06273, South Korea
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