New hope for rare liver disease: experimental drug GS-4321 enters human trials

NCT ID NCT07096193

First seen Oct 31, 2025 · Last updated May 12, 2026 · Updated 28 times

Summary

This study tests a new drug called GS-4321 for chronic hepatitis delta, a serious liver infection. First, healthy volunteers will help determine safe dosing. Then, people with the infection will receive the drug to see if it reduces virus levels and improves liver health. The goal is to control the disease, not cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chang Gung Medical Foundation Kaohsiung Chang Gung Memorial Hospital

    RECRUITING

    Kaohsiung City, 83301, Taiwan

  • Fundatia Dr. Victor Babes

    RECRUITING

    Bucharest, 030303, Romania

  • Gastromedica S.R.L.

    RECRUITING

    Iași, 700506, Romania

  • IMSP Spitalul Clinic de Boli Infectioase "Toma Ciorba"

    RECRUITING

    Chinsinau, 2004, Moldova

  • Infectious Diseases Institutul National De Boli Infectioase Prof. Matei Bals

    RECRUITING

    Bucharest, 21105, Romania

  • Institutul National De Boli Infectioase Prof. Dr. Matei Bals

    RECRUITING

    Bucharest, 021105, Romania

  • Investigative Site

    RECRUITING

    Anaheim, California, 92801, United States

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    RECRUITING

    Kaohsiung City, 807, Taiwan

  • Korea University Ansan Hospital

    RECRUITING

    Ansan-si, 425-707, South Korea

  • PMSI Clinical Republican Hospital "Timofei Mosneaga"

    RECRUITING

    Chisinau, MD-2025, Moldova

  • Samsung Medical Center

    RECRUITING

    Seoul, 135-710, South Korea

  • The Catholic University of Korea Bucheon St. Mary's Hospital

    RECRUITING

    Bucheon-si, 14647, South Korea

  • The Catholic University of Korea, Seoul St. Mary's Hospital

    RECRUITING

    Seoul, 06591, South Korea

  • The New York-Presbyterian Hospital

    RECRUITING

    New York, New York, 10021, United States

  • University of Maryland, Institute of Human Virology, Clinical Research Unit

    RECRUITING

    Baltimore, Maryland, 21201, United States

Conditions

Explore the condition pages connected to this study.