Fox Chase Cancer Center

This study is testing a different way of taking the drug cabozantinib to see if it can reduce severe side effects while still controlling cancer growth. It involves 111 adults with advanced kidney cancer or neuroendocrine tumors. The goal is to find a dosing schedule that patient…

This early-phase study tests whether giving extra, MRI-guided radiation after standard treatment is safe for people with rectal cancer. About 37 participants will first receive standard chemoradiation, then get additional radiation that adjusts every two weeks based on tumor chan…

This study tests a new way to give radiation for prostate cancer that adapts to your body shape each day. The goal is to safely give a higher dose to the cancer while protecting nearby organs. About 80 adults with intermediate- or high-risk prostate cancer will receive 5 treatmen…

This early-phase trial tests a type of radiation that adapts to the tumor's shape and position, allowing higher doses to be delivered safely. It enrolls 30 adults with cancer that has spread to the abdomen or pelvis. The goal is to improve tumor control while keeping severe side …

This early-phase trial tests whether adding an experimental skin injection (CADI-05) to standard immunotherapy (pembrolizumab) can help the immune system better fight advanced head and neck cancer before surgery. About 22 adults with resectable, locally advanced disease will rece…

This study tests a two-step treatment for people with advanced bladder cancer that has spread. First, patients receive a combination of two drugs (enfortumab vedotin and pembrolizumab) for 18 weeks. Then, those who respond well continue with just pembrolizumab for up to 2 years t…

This early-phase trial tests a combination of two targeted drugs, neratinib and fam-trastuzumab deruxtecan (Enhertu), in people with advanced stomach, esophageal, or other gastrointestinal cancers that have a specific marker called HER2. Participants must have already tried at le…

This study is testing whether a combination of a blood test and a urine test can detect aggressive muscle-invasive bladder cancer that standard scopes might miss. About 92 people scheduled for bladder removal surgery will provide samples before their operation. If the tests prove…

This early study is testing whether CBD supplements can prevent nerve damage caused by a common chemotherapy drug. Researchers will give CBD capsules to some colorectal cancer patients during their treatment to see if it protects their nerves. The study focuses on whether patient…

This study tests whether Adaptive Radiation Therapy (ART) can better target aggressive pancreatic cancer cells while protecting nearby healthy tissue. About 16 people with locally advanced, inoperable pancreatic cancer will receive 5 radiation treatments over 2 weeks. The main go…

This study aims to help Asian American cancer patients and their caregivers feel better emotionally by testing a program of positive activities. The program is designed to boost feelings of independence, confidence, and connection. About 186 patient-caregiver pairs will take part…

This study tests whether an educational video and workbook can help gynecologic cancer patients bring up sexual health concerns with their doctors. About 200 patients will either receive the video and a resource booklet, or just the booklet with usual care. Researchers will compa…

This study aims to understand the genetic and molecular causes of breast and prostate cancer in people of African ancestry. Researchers will collect blood and tumor samples from 1,500 participants across nine countries and the US, along with information about lifestyle and social…