Personalized radiation aims to outsmart tough pancreatic tumors

NCT ID NCT06984562

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests whether adaptive radiation therapy (ART) can safely deliver higher, more focused radiation doses to pancreatic tumors while protecting nearby organs. Sixteen adults with locally advanced, inoperable pancreatic cancer will receive five treatments over two weeks. The main goal is to check for serious side effects, with secondary goals of seeing if the tumor stays controlled and how long patients live.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Adaptive Radiation Therapy (ART)

What this could lead to

If successful, this approach could make radiation therapy safer and more effective for people with inoperable pancreatic cancer, potentially improving local tumor control and quality of life.

What could go wrong

This is a very early, small Phase I trial with only 16 participants. It primarily tests safety and dosing, not effectiveness. The cancer is advanced and hard to treat, so benefits may be limited.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fox Chase Cancer Center

    RECRUITING

    Philadelphia, Pennsylvania, 19111, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••