New study aims to cut side effects in throat cancer treatment
NCT ID NCT05800574
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase II trial is testing whether giving radiation only to the side of the neck where the cancer is found can reduce dry mouth and other side effects in people with HPV-positive oropharynx cancer. About 22 participants will receive radiation (with or without chemotherapy) to just one side of the neck. The main goal is to see if the cancer stays away from the untreated side within a year after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Radiation therapy and cisplatin chemotherapy
- What this could lead to
- If successful, this approach could reduce long-term dry mouth and other side effects for patients with HPV-related throat cancer, while still controlling the disease.
- What could go wrong
- This is a small, early-phase study with only 22 participants, so results may not apply to everyone. There is a risk that cancer could spread to the untreated side of the neck.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fox Chase Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19111, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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