Simple DNA test could reveal hidden bladder cancer before surgery
NCT ID NCT06396533
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a combined blood and urine DNA test can accurately detect muscle-invasive bladder cancer in patients scheduled for bladder removal surgery. Researchers will compare the test results with the actual findings from surgery. The goal is to see if this non-invasive test can help doctors decide on the best surgical approach. About 92 adults with various stages of bladder cancer are being enrolled.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- blood and urine DNA test (ctDNA and cfDNA assay)
- What this could lead to
- If successful, this test could help doctors better identify which bladder cancer patients need more aggressive surgery, potentially improving outcomes.
- What could go wrong
- This is an early-stage diagnostic trial with only 92 participants, so the test may not be accurate enough for widespread use. It is not a treatment and does not directly improve survival.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fox Chase Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19111, United States
-
University of Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 68198, United States
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