New combo therapy aims to keep advanced bladder cancer at bay

NCT ID NCT07221942

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 30 times

Summary

This study tests a two-step treatment for people with advanced bladder cancer that has spread. First, patients receive a combination of two drugs (enfortumab vedotin and pembrolizumab) for 18 weeks. Then, those who respond well continue with just pembrolizumab for up to 2 years to help keep the cancer from coming back. The goal is to see if this approach improves survival without the cancer progressing.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fox Chase Cancer Center - Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19111-2497, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.