Fox Chase Cancer Center

This study tests whether giving the drug enfortumab vedotin less often can still control advanced bladder cancer while reducing side effects. About 60 adults with metastatic or locally advanced urothelial carcinoma will receive the drug alone or with pembrolizumab. The goal is to…

This study tests a modified chemotherapy regimen for people aged 65 and older with newly diagnosed metastatic pancreatic cancer. The treatment alternates between two drug combinations (FOLFOX and FOLFIRI) to see if it is easier to tolerate than the standard FOLFIRINOX regimen. Th…

This early-phase study tests a new way to treat advanced solid tumors by combining low-dose radiation with a drug called 5-aminolevulinic acid (ALA). ALA helps cancer cells absorb more radiation, potentially killing them while sparing healthy tissue. The study involves 130 adults…

This study tests a combination of two drugs, nivolumab and ramucirumab, in people with advanced non-small cell lung cancer that has come back or spread. Participants have already received immunotherapy. The main goal is to see if the combination can control the disease by shrinki…

This study tests a combination of two drugs, nivolumab and axitinib, in people with advanced kidney cancer. The goal is to find the safest dose and see how well the drugs shrink tumors. About 98 participants, both previously treated and untreated, will take part. The study is in …