Columbia University

This study is testing whether adding a special processed tissue from human placentas to a standard rotator cuff repair surgery helps the tendon heal better to the bone. The goal is to see if this reduces the chance of the shoulder re-tearing after surgery. About 120 adults with a…

This study aims to find the best treatment for a first-time kneecap dislocation. Researchers will compare surgery to reconstruct a knee ligament against a standard physical therapy program. They will measure which approach better prevents the kneecap from dislocating again and le…

This study aims to find the best treatment for a first-time dislocated shoulder. It will randomly assign 200 participants to either have a minimally invasive surgical repair or follow a physical therapy program. Researchers will track which group has fewer repeat dislocations and…

This study is testing a small implanted device called Barostim in adults with severe heart failure who still have symptoms despite taking all recommended medications. The device stimulates nerves in the neck to help balance the body's automatic systems and improve how the heart w…

This study aims to find out if adding a strong, tape-like 'internal brace' to a standard ACL knee surgery helps people recover faster and have better long-term knee stability. Researchers will compare two groups of 200 patients with ACL tears: one group gets the standard surgery,…

This study is testing whether a gentle red light treatment, called photobiomodulation, can help improve the development of eggs and embryos during IVF. The light aims to boost the energy levels in eggs, which can decline with age, potentially leading to better quality embryos and…

This study will test if placing a single, cost-effective HEPA air cleaner in the home can help children with asthma breathe easier. Researchers will monitor air quality and children's lung function for a year in 55 homes in East Harlem, NYC. The goal is to see if cleaner air redu…

This study aims to find the most accurate way to test if the living tissue inside a tooth is healthy before starting a root canal. Researchers will compare a new laser-based blood flow test against two standard methods that rely on a patient feeling pain from cold or electricity.…

This study aims to find undiagnosed or poorly controlled high blood pressure and glaucoma in adults aged 40 and older living in New York City affordable housing. Researchers will screen over 7,000 people and test if a virtual assistant that sends reminders and health information …

This study is testing whether artificial intelligence (AI) can help heart doctors read ultrasound scans of the heart more quickly and consistently. It will involve 50 cardiologists at Columbia University who will use the AI tool while reviewing patient scans. The goal is to see i…

This study aims to see if health messages created by sex trafficking survivors themselves can encourage more survivors to get tested for HIV, STIs, and Hepatitis C, and to use overdose prevention kits. The research team will work with survivors to design these messages and then t…

This study is testing if a special live music program can help reduce chronic stress in pregnant Black women, with the goal of lowering the risk of preterm birth. Researchers will compare the music program to a simple talk session. They aim to see if reducing stress through music…

This study aims to see if monitoring brain waves during surgery can help doctors better adjust pain medication to reduce confusion and delirium in older patients after their operation. Researchers will recruit 600 adults aged 60+ undergoing elective non-cardiac surgery lasting at…

This large study aims to find out if a drug called ketamine works as well as the standard morphine for treating severe pain in children who come to the emergency room with a broken bone or bad stomach ache. Researchers want to see if ketamine causes fewer serious side effects lik…

This study is testing whether a new mindfulness-based therapy helps reduce PTSD symptoms in people who survived cardiac arrest. Researchers will compare this therapy against another established talk therapy to see which works better. Participants will receive 12 weeks of individu…

This study is testing a new smartphone app called iBlink to understand how exercise affects the brain in people with spinocerebellar ataxia, a disabling movement disorder. Researchers want to see if aerobic exercise improves a specific type of motor learning measured by the app, …

This early-stage study aims to understand if lowering high insulin levels for one week can reduce the liver's production of new fat, a key driver of fatty liver disease. Researchers will compare a drug called diazoxide against a placebo in 25 adults with obesity, insulin resistan…

This study aims to understand how high insulin levels contribute to fatty liver disease in people who are overweight and insulin resistant. Researchers will temporarily control insulin levels in 36 participants to measure how the liver produces fat and sugar. The goal is to gathe…