Could ketamine replace morphine for kids in pain?
NCT ID NCT06835504
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares ketamine to morphine for treating acute pain in children visiting the emergency department. Over 1,000 children with abdominal pain or broken bones will receive either drug. The goal is to see if ketamine works as well as morphine but with fewer side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ketamine hydrochloride and morphine sulphate
What this could lead to
If ketamine works as well as morphine, it could offer a safer, non-opioid option for managing acute pain in children.
What could go wrong
This is a non-inferiority trial, so ketamine might not be as effective as morphine. Side effects from ketamine are also possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Arthur M. Blank Hospital
Atlanta, Georgia, 30329, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Children's Wisconsin
Milwaukee, Wisconsin, 53226, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nemours Children's Hospital
Wilmington, Delaware, 19803, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NewYork Presbyterian Morgan Stanley Children's Hospital
New York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Seattle Children's Hospital
Seattle, Washington, 98105, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UC Davis Children's Hospital
Sacramento, California, 95817, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15224, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••