PEDIATRICS

This study tests whether a high-energy diet helps infants with congenital heart disease grow and develop their brains better after heart surgery. Researchers will compare high-energy versus standard nutrition in 160 babies aged 0-6 months. The goal is to see if the special diet i…

This study looks at whether giving less intravenous (IV) fluid to critically ill children with traumatic injuries leads to fewer complications. Currently, there is no standard for how much fluid these children should receive. The trial will enroll 250 children aged 6 months to 15…

This study tests whether parent coaching via video calls (Tele-PCIT) can help young children with disruptive behavior who are also at risk for trauma. About 50 families with children aged 2 to 6 will receive weekly one-hour coaching sessions over 12-16 weeks. The goal is to impro…

This study tests two types of post-discharge support for children with special healthcare needs. One group gets a single follow-up phone call within 72 hours of leaving the hospital, while the other gets more ongoing support. Researchers want to see which approach reduces emergen…

This study tests a special dye called Cytalux that makes cancer cells glow under near-infrared light. Surgeons use it during lung surgery to find and remove hard-to-see tumors in teens (ages 6-17) with bone cancer that has spread to the lungs. The goal is to see if the dye helps …

This study is testing a device called ViBandz, which uses small vibrating motors strapped to the body to provide vibration therapy. Researchers want to see if it is easy and comfortable for children with neurological conditions to use at home. The study will involve 30 children a…

This pilot study tests whether a topical diclofenac gel (Voltaren) works as well as oral ibuprofen for reducing pain in children aged 6-18 with ankle or knee sprains. Sixty participants will use either the gel or oral medicine three times a day for three days, then report their p…

This study follows healthy girls ages 8-14 and teens with irregular periods to learn how their menstrual cycles become regular after their first period. Researchers also include girls at risk for PCOS and compare them to women with and without PCOS. The goal is to understand norm…

This study will track 10,000 children admitted to pediatric intensive care units (ICUs) across Asia. The goal is to understand what factors lead to better or worse outcomes, and to develop AI tools that can predict how long a child might need ICU care or their risk of death. No n…

This study looks at whether a new way of scoring whole-body MRI scans can reliably measure bone inflammation in children with CRMO, a rare condition causing repeated bone pain and swelling. Researchers will compare the MRI scores from different doctors and also check if changes i…

This study tests whether a machine learning model can predict which children admitted to the hospital will need a medication that requires genetic testing. The goal is to offer the test earlier, so doctors can pick the safest drug or dose. The trial will involve 275 children aged…

This study looks at how seizures change the brain's wiring in children with drug-resistant focal epilepsy. Researchers will use special EEG recordings and MRI scans to measure brain connections in 82 children. The goal is to understand if ongoing seizure activity causes lasting d…

This study looks at how often children develop low blood sugar (hypoglycemia) after fasting before anesthesia for elective procedures. Researchers will monitor blood sugar levels in over 6,500 children aged 1 month to 18 years to find a clear definition of hypoglycemia and identi…

This study aims to create and validate a Turkish version of a short neurological exam called the BRIEF-HINE for babies at high risk of brain problems. Researchers will test 120 infants aged 3 to 12 months who have conditions like premature birth or brain injury. The goal is to se…