Columbia University

This study tested a drug called siplizumab alongside a stem cell transplant for people with severe sickle cell disease. The goal was to see if it could prevent the body from rejecting the new cells and reduce a serious side effect called graft-versus-host disease. Only one person…

This study looked at whether tesamorelin (Egrifta), a daily injection that boosts growth hormone, can improve body composition in people with HIV who have excess belly fat (lipodystrophy). Six participants received the drug for up to 12 months, with researchers measuring liver fa…

This study looked at whether taking high doses of statins for two weeks before carotid artery surgery could prevent memory and thinking problems after the operation. It included 31 adults with severe carotid artery narrowing. The study was stopped early, so the results are limite…

This study tested a new way to manage blood pressure in new mothers with severe postpartum preeclampsia. Participants received standard blood pressure medications, but one group had personalized blood pressure targets based on real-time brain monitoring. The goal was to keep bloo…

This study tested a radioactive tracer called Annexin to see if it can detect early lung damage in people with COPD and in smokers. Researchers compared scans from healthy non-smokers, healthy smokers, and people with moderate to severe COPD. The goal was to find a better way to …

This study tested a mobile app called Apricity CARE to help ethnic and racial minority patients with non-small cell lung cancer report side effects from immunotherapy. The goal was to reduce treatment delays and hospital visits. The study was stopped early, but it aimed to improv…

This study aimed to compare two blood pressure medications—oral nifedipine (a pill) and intravenous labetalol (given through a vein)—for treating dangerously high blood pressure in women who have just given birth. The goal was to see which drug lowers blood pressure faster. Howev…

This study looked at how insulin works in the skin of people with plaque psoriasis who are also overweight or have prediabetes. Researchers took small skin samples from both psoriasis patches and healthy skin to measure insulin activity. The goal was to understand if insulin acts…

This study aimed to create a program to help people at risk for suicide stay in mental health treatment. Researchers planned to interview patients and staff, then test a new approach using shared decision-making, phone outreach, and peer support. However, the study was terminated…