Columbia University
Clinical trials sponsored by Columbia University, explained in plain language.
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New drug aimed at making risky sickle cell transplants safer
Disease control TerminatedThis study tested whether adding a drug called siplizumab to a stem cell transplant could make the procedure safer and more effective for adults with severe sickle cell disease. The main goal was to see if the drug could prevent the donor cells from being rejected (graft failure)…
Phase: PHASE1, PHASE2 • Sponsor: Columbia University • Aim: Disease control
Last updated Apr 01, 2026 21:37 UTC
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Brain monitor could protect new moms from stroke risk
Disease control TerminatedThis study tested whether personalized blood pressure targets could better protect new mothers from brain injury after preeclampsia. Researchers used a special brain monitor to set individual blood pressure goals for 26 women in the hospital. The trial was stopped early, so resul…
Phase: NA • Sponsor: Columbia University • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New approach aims to keep High-Risk patients connected to lifesaving care
Prevention TerminatedThis study aimed to create a practical program to help people at risk of suicide stay engaged in outpatient mental health treatment. Researchers interviewed patients and staff to understand what helps or hinders treatment attendance, then designed a pilot program based on that fe…
Phase: NA • Sponsor: Columbia University • Aim: Prevention
Last updated Mar 27, 2026 12:39 UTC
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Scientists test 'Apoptosis Tracer' to spot hidden lung damage in smokers and COPD
Knowledge-focused TerminatedThis study tested a new radioactive imaging agent called Annexin to see if it could detect early lung cell damage in people with COPD and in healthy smokers. Researchers compared scans from 34 participants, including healthy non-smokers, healthy smokers, and people with moderate …
Phase: PHASE2 • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists probe surprising link between skin patches and blood sugar
Knowledge-focused TerminatedThis small, terminated study aimed to understand the connection between psoriasis and diabetes. Researchers took small skin samples from 10 people with plaque psoriasis to check how insulin acts in their skin patches. The goal was to see if this could explain why people with psor…
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC