New drug combo aims to make stem cell transplants safer for sickle cell patients

NCT ID NCT06078696

First seen Mar 18, 2026 · Last updated May 14, 2026 · Updated 6 times

Summary

This study tested whether adding the drug siplizumab to a stem cell transplant could prevent graft failure and graft-versus-host disease in people with advanced sickle cell disease. Only one person enrolled before the study was stopped early. The goal was to make transplants safer and more effective for this serious blood disorder.

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Contacts and locations

Locations

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States

Conditions

Explore the condition pages connected to this study.