Sickle cell hope: drug combo raises hemoglobin in early trial

NCT ID NCT05451940

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether adding erythropoietin (EPO) to the standard drug hydroxyurea can safely raise hemoglobin levels in adults with sickle cell disease. Seventeen participants with chronic anemia took both drugs for 12 weeks. The main goal was to see if at least a 1.0 g/dL increase in hemoglobin occurred, while also tracking transfusion needs.

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Conditions

The condition(s) this trial relates to.

anemia sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Lagos University Teaching Hospital

    Lagos, 102215, Nigeria

  • UPMC

    Pittsburgh, Pennsylvania, 15213, United States