Children's Hospital Of Philadelphia

This study is testing a new set of resources designed to help both teachers and parents use proven behavioral strategies to support children showing signs of ADHD. It involves 100 children in kindergarten through 5th grade. Researchers will compare classrooms where only teachers …

This project aims to reduce unnecessary antibiotic use for common childhood infections like earaches, strep throat, sinus infections, and pneumonia. It will provide education, feedback, and tools to doctors and nurses across a large children's hospital network to help them prescr…

This trial is testing a modified stem cell transplant for people with blood cancers like leukemia and lymphoma who don't have a perfectly matched donor. Doctors use a special process to remove certain immune cells from the donor's stem cells before the transplant. The goal is to …

This pilot study is testing whether adding a trained community health worker to the healthcare team can help children newly diagnosed with type 1 diabetes and their families. The community health worker provides personalized support for one year, helping families navigate challen…

This study is testing a combined therapy and support program for mothers who are in treatment for substance use and have a young child (from pregnancy up to age 5). The goal is to improve child safety and well-being, strengthen the parent-child bond, and reduce the risk of the ch…

This study is testing a fetal surgery procedure to help babies with a severe form of congenital diaphragmatic hernia (CDH) survive after birth. In severe CDH, a hole in the diaphragm allows organs to press on the lungs, preventing them from growing properly. Doctors temporarily p…

This study is testing a new hospital program designed to make sure children get the right antibiotic prescriptions when they go home. It focuses on kids with common infections like pneumonia, UTIs, and skin infections. The program involves creating clear guidelines for doctors an…

This study is testing a modified stem cell transplant procedure for children and young adults with life-threatening immune system disorders. It uses a special processing method on stem cells from partially matched family donors or unrelated donors to reduce complications. The mai…

This study aimed to create a new educational app for parents of children aged 8-12 with type 1 diabetes. Researchers wanted to understand what support parents need to better use insulin pumps and glucose monitors. The goal was to help families improve daily diabetes management, b…

This small pilot study is testing whether a less invasive procedure to reduce stomach size is safe and effective for weight loss in adolescents with obesity. Up to 10 teens will have the endoscopic procedure, which uses a scope instead of surgery, and will be closely monitored fo…

This study is testing whether a quick, safe ultrasound of a baby's neck can predict if placing a breathing tube will be difficult during surgery. Researchers will scan 180 babies under 1 year old before their procedures to see if certain ultrasound measurements match up with how …

This study is testing a radiation-free ultrasound method to find internal injuries in children under 8 who have had a blunt force to the abdomen, such as from a fall or car accident. Researchers are comparing this new scan to the current standard CT scan to see if it is just as a…

This study aims to see if a simple urine test, originally developed for adults, can accurately detect early signs of rejection or infection in children who have received a kidney transplant. It involves 445 children and teens, aged 2 to 18, who have had a transplant. The goal is …

This study is testing whether a resilience coaching program can help teenagers with long-term muscle and joint pain. Researchers are comparing teens who receive the coaching plus usual care to those who receive only usual care. They want to see if coaching improves how teens func…

This pilot study is testing whether a daily meditation practice can help patients feel less pain and anxiety before and after surgery to remove kidney stones. Researchers will randomly assign 50 patients (ages 12 and up) to either learn meditation or receive usual care. The goal …

This study aims to see if using an ultrasound scan on a child's stomach before urgent trauma surgery can accurately identify those with a lot of fluid or food still present. Researchers want to understand which injured children are at higher risk for stomach contents accidentally…

This study is testing two different approaches to help pediatric intensive care units reduce unnecessary blood culture tests. Researchers are working with eight pediatric ICUs to see which strategy works better at lowering test rates while maintaining patient safety. The goal is …

This study aims to understand the biological and genetic reasons why some people develop food allergies and why many children outgrow them. Researchers will collect blood samples from about 5,300 participants, including people with food allergies and healthy family members, to an…

This study aims to find the best ways to help hospitals stop using continuous oxygen monitors on infants with bronchiolitis who are breathing well without extra oxygen. Researchers are testing different approaches across multiple hospitals with nearly 10,000 infant observations. …

This study aims to better understand mitochondrial diseases by using a special MRI scan to measure how well muscles produce energy. Researchers will scan the legs of about 230 people, including patients with the disease and healthy volunteers, while they perform a simple foot-ped…