Gentler bone marrow transplant shows promise for kids with blood disorders

NCT ID NCT01050855

First seen May 11, 2026 ยท Last updated May 11, 2026

Summary

This study tests a milder chemotherapy regimen before a bone marrow or cord blood transplant in children and young adults (ages 6 months to 25 years) with non-cancerous blood disorders like sickle cell disease, thalassemia, and immune deficiencies. The goal is to see if this gentler approach helps donor cells successfully engraft while causing fewer side effects than standard transplants. The study is active but no longer recruiting new participants.

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Contacts and locations

Locations

  • The Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.