IMMUNODEFICIENCIES
Clinical trials for IMMUNODEFICIENCIES explained in plain language.
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New stem cell processing method offers hope for patients without a perfect donor match
Disease control AVAILABLEThis expanded access protocol provides stem cell transplants for people with serious blood diseases like leukemia, bone marrow failure, or immune deficiencies who do not have a fully matched sibling donor. The donated stem cells are processed to remove certain immune cells (alpha…
Matched conditions: IMMUNODEFICIENCIES
Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Second chance: milder prep for stem cell transplants may help when first fails
Disease control Recruiting nowThis trial tests a second stem cell transplant using a gentler conditioning regimen of busulfan, fludarabine, and low-dose total body irradiation. It is for people with blood disorders, hemoglobin diseases, or immune deficiencies whose first transplant did not achieve enough dono…
Matched conditions: IMMUNODEFICIENCIES
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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New stem cell transplant option for patients without a perfect donor match
Disease control Recruiting nowThis expanded access program offers a stem cell transplant using donor cells that have been specially processed to remove certain immune cells, reducing the risk of graft-versus-host disease. It is for patients with serious blood disorders, immune deficiencies, or metabolic disea…
Matched conditions: IMMUNODEFICIENCIES
Phase: EARLY_PHASE1 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New IVIG therapy V-IMMUNE tested in phase III trial for immune deficiency
Disease control Recruiting nowThis phase III trial tests V-IMMUNE, an intravenous immunoglobulin (IVIG) product, in about 50 people with primary immunodeficiency (PID). Participants, aged 2 and older, will switch from their current IVIG to V-IMMUNE every three weeks for a year. The study aims to see if V-IMMU…
Matched conditions: IMMUNODEFICIENCIES
Phase: PHASE3 • Sponsor: On Pharma Importadora, Exportadora e Distribuidora de Medicamentos LTDA. • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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NIH launches massive study to unlock HIV's secrets through blood
Knowledge-focused Recruiting nowThis study aims to learn more about how HIV infects cells and affects the immune system by collecting blood samples from up to 2,419 adults, both with and without HIV. Researchers will analyze these samples to compare genetic and protein differences. The goal is to better underst…
Matched conditions: IMMUNODEFICIENCIES
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC