Central Hospital, Nancy, France
Clinical trials sponsored by Central Hospital, Nancy, France, explained in plain language.
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New antibiotic approach may cut infections after pancreatic surgery
Disease control CompletedThis study looked at 117 patients who had pancreatic surgery to see if changing the antibiotic given before surgery could reduce infections. The researchers compared an older antibiotic (cephalosporin) with a newer one (piperacillin/tazobactam) based on local bacteria patterns. T…
Sponsor: Central Hospital, Nancy, France • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Heart scans could spare patients from invasive catheter procedures
Diagnosis CompletedThis study compares cardiac MRI to the standard right heart catheterization for monitoring people with pulmonary arterial hypertension (PAH), a condition that strains the heart. Researchers want to see if the non-invasive MRI can reliably detect when a patient's condition is wors…
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jul 02, 2026 01:00 UTC
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New 25-Minute bone scan could spot cancer faster with less radiation
Diagnosis CompletedThis study tested a new 3D bone scan camera (VERITON-CT) that takes only 25 minutes and uses less radiation than standard scans. Researchers compared it to conventional 2D scans in 146 people with suspected or known bone metastases. The goal was to see if the new method could acc…
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 14:03 UTC
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New scan technique could reveal hidden COVID-19 lung signs
Diagnosis CompletedThis study looked at whether PET-CT scans can detect unique signs of COVID-19 in the lungs. Researchers scanned 22 patients suspected of having lung infections and compared the images to their COVID-19 test results. The goal was to find patterns that could help diagnose COVID-19 …
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 14:03 UTC
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New PET tracer could spot hidden heart inflammation
Diagnosis CompletedThis study tested whether a special PET scan using 68Ga-DOTATOC can detect inflammation in the heart muscle of people with myocarditis. 33 adults with suspected acute myocarditis and normal angiograms received the scan. The goal was to see if this method is as good as or better t…
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 14:03 UTC
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Brain scans may sharpen diagnosis of cognitive disorders
Diagnosis CompletedThis study looked at whether a special brain scan called 18F-FDG PET can help doctors tell the difference between cognitive problems caused by psychiatric conditions versus neurodegenerative diseases like Alzheimer's. Researchers studied 20 adults with cognitive impairment who ha…
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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AI reads brain scans to spot Parkinson's early
Diagnosis CompletedThis study tested whether artificial intelligence (AI) can help diagnose Parkinson's disease by analyzing brain scans called DaTSCAN SPECT. Researchers used machine learning to tell the difference between healthy people, those with Parkinson's, and those with similar conditions. …
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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Blood test could unlock stroke treatment for thousands
Diagnosis CompletedThis study looked at whether measuring two proteins in the blood (GST-π and PRDX1) can accurately determine if a stroke occurred within the last 4.5 hours. That time window is critical because it determines if patients can receive clot-busting medication. Researchers enrolled 935…
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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Tiny study hints at imaging tool to predict meningioma treatment success
Diagnosis CompletedThis completed study looked at 11 patients with meningioma (a type of brain tumor) who received a treatment called 177Lu-DOTATATE. Researchers used special scans to measure how much radiation the tumors absorbed, and checked if that could predict whether patients would survive wi…
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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New imaging tool could help spot cancerous bone tumors earlier
Diagnosis CompletedThis study tested a new structured reporting system called BTI-RADS to help doctors better assess bone tumors from X-rays, CT, and MRI scans. Researchers analyzed images from 1,100 patients to see if the tool could more accurately tell which tumors are likely cancerous. The goal …
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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MRI may spare babies radiation in kidney blockage diagnosis
Diagnosis CompletedThis study looked at whether functional MRI can accurately measure kidney function in children with pyelo-ureteral junction syndrome, a common urinary blockage. Researchers compared MRI results to the standard scintigraphy scan in 270 children aged 0-17. The goal was to see if MR…
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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New blood test may spot liver cancer sooner in High-Risk patients
Diagnosis CompletedThis study looked at 639 adults with cirrhosis to see if a blood test called mSEPT9 can detect liver cancer (hepatocellular carcinoma) better than the current standard test (AFP). Participants gave an extra blood sample during routine care, and researchers compared how well each …
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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Blood cell count may reveal who faces worst outcomes in rare autoimmune disease
Diagnosis CompletedThis study examined whether the level of neutrophils, a type of white blood cell, in the blood can help predict how severe antisynthetase syndrome (ASyS) will be. ASyS is a rare autoimmune disease that can cause muscle inflammation, lung disease, and other symptoms. Researchers l…
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 12:10 UTC
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No-Needle MRI shows promise for Crohn's monitoring
Diagnosis CompletedThis study tested whether a quick MRI without contrast injection can spot signs of Crohn's disease as well as the standard MRI with contrast. 250 patients were scanned using both methods, and radiologists compared the results. If the injection-free approach works, it could make f…
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 09:00 UTC
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Which test best uncovers the sleeping parasite?
Diagnosis CompletedThis study looked at three different blood tests (ELISA) for diagnosing strongyloidiasis, an infection caused by a parasite that can stay hidden in the body. Researchers tested 80 adult patients who had previously had a positive or borderline result. The goal was to see which tes…
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC
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Blood test may speed up deadly fungal infection diagnosis
Diagnosis CompletedThis study looked at a blood test called Beta-D-glucan (BDG) to see how well it detects invasive fungal infections in people with weak immune systems. Researchers tested 280 patients and checked if two positive results within 15 days confirmed an infection. The goal is to help do…
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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Faster, sharper fungal diagnosis: PCR kits put to the test
Diagnosis CompletedThis study looked at 120 people with suspected fungal skin infections (like athlete's foot or nail fungus). Researchers compared two different PCR test kits to see how well they could detect the fungus compared to standard lab methods. The goal was to find a faster and more relia…
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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AI could make bone scans faster and sharper
Knowledge-focused CompletedThis completed study tested whether an artificial intelligence algorithm can reduce noise in fast whole-body bone scans, potentially allowing shorter scan times. Researchers compared images processed by the AI to those processed with a traditional filter. The study involved 20 pa…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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New PET scan method could better track brain tumor treatment success
Knowledge-focused CompletedThis study looked at whether a special type of PET scan (amino acid PET) can better measure how well IDH inhibitor drugs are working in patients with a certain type of brain tumor (IDH-mutated glioma). The researchers compared the PET scan results with standard MRI scans in 22 pa…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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New imaging database aims to sharpen Parkinson's diagnosis
Knowledge-focused CompletedThis completed study created the first international database of Datscan imaging values from 300 patients. The goal was to help doctors better diagnose Parkinson's disease and other neurodegenerative conditions by comparing brain scan results. Researchers hope this database will …
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Ports may offer easier way to deliver prostate cancer drug
Knowledge-focused CompletedThis study tested whether Pluvicto, a radioactive drug for prostate cancer, can be safely given through a permanently implanted port (TIVAP) instead of a standard IV. Researchers measured if any drug got stuck in the port in 107 patients. The goal was to see if using the port is …
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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New camera could make cancer treatment safer by better tracking radiation
Knowledge-focused CompletedThis study tested whether a new type of camera (VERITON-CT) can accurately measure radiation doses in patients receiving Lutathera, a treatment for certain cancers. Fifteen adults were scanned with both the new camera and a standard camera at different times after treatment. The …
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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New imaging method could reduce need for brain tumor biopsies
Knowledge-focused CompletedThis completed study looked at whether a special PET scan technique called radiomics can help doctors figure out the type and behavior of brain tumors (gliomas) without needing a surgical biopsy. Researchers analyzed scans from 1000 patients who had already received an 18F-FDOPA …
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Blood tests may unlock secrets of heart failure in metabolic syndrome
Knowledge-focused CompletedThis completed study looked at blood samples from 47 patients in France (part of a larger European study) to find biological markers linked to diastolic heart failure in people with metabolic syndrome. The goal was to confirm earlier findings about these markers. Participants had…
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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New imaging comparison could improve prostate cancer monitoring
Knowledge-focused CompletedThis completed study looked at 80 patients with advanced prostate cancer that had stopped responding to chemotherapy. All patients received a radioactive drug called 177Lu-PSMA-617. Researchers compared two types of scans—PET and SPECT—to see which better tracks changes in tumor …
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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PET scans reveal hidden brain changes in young COVID survivors
Knowledge-focused CompletedThis completed study looked at 25 young adults (ages 18-65) who had severe COVID-19 and now have thinking or memory problems. Researchers used a special PET-CT scan to see if there are changes in brain activity and how that relates to lung damage. The goal was to better understan…
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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PET scans outshine older method for rare ear infection?
Knowledge-focused CompletedThis study compared two imaging methods—PET/CT and labeled leukocyte scintigraphy—for monitoring malignant otitis externa, a serious infection of the ear canal that can spread to the skull. Researchers looked at 18 patients who had both scans before and after antibiotic treatment…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Can pictures of smells cure motion sickness in virtual reality?
Knowledge-focused CompletedThis study looked at how different visual prompts—like words, pictures, or colors—activate the brain's smell center in 30 healthy adults. Using fMRI scans, researchers aimed to find the best way to trigger a sense of smell through imagination. The goal is to use this knowledge to…
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New program aims to cut frequent ER visits and costs
Knowledge-focused CompletedThis study tested a program called DAUM for adults who visit the emergency department at least four times a year. The program connects them with a support team to create a personalized health and social plan. Researchers measured whether the program reduced ER visits and saved mo…
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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CT scan study reveals possible link between nose and jaw problems
Knowledge-focused CompletedThis study examined CT scans from 223 adults to see if a deviated nasal septum (a crooked wall inside the nose) is related to a narrow upper jaw (maxillary transverse deficiency). The goal was to understand if these two conditions are connected, which could help doctors decide wh…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Wisdom teeth may hold key to simpler orthodontic decisions
Knowledge-focused CompletedThis study looked at 200 healthy people to see if the growth stage of upper wisdom teeth (third molars) on X-rays matches the maturity of the midpalatal suture—a bone seam in the roof of the mouth that guides orthodontic treatment. Researchers used cone beam CT scans and X-rays t…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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MRI scans could replace invasive heart tests for lung disease patients
Knowledge-focused CompletedThis study looked at whether cardiac MRI can accurately measure right heart function in 112 people with pulmonary arterial hypertension. Researchers compared MRI results with data from invasive heart catheterization. The goal was to see if MRI could be used to monitor disease and…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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What brings people to the dental ER? new study analyzes 611 cases
Knowledge-focused CompletedThis study looked at 611 patients who came to the dental emergency department at the University Hospital of Nancy through a special access clinic. Researchers wanted to understand what types of dental emergencies people had, when they came in, and how much the care cost. The goal…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Healthy volunteers help sharpen MRI technology
Knowledge-focused CompletedThis study aimed to make MRI scans clearer and more reliable. Researchers tested new imaging methods on 1,807 healthy adults to improve picture quality and reduce blurring. No treatment or medication was given—the goal was simply to gather knowledge to help future patients.
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Hospitalization as a golden moment to start heart failure drugs
Knowledge-focused CompletedThis study involved 184 adults hospitalized for worsening heart failure. Researchers tracked which heart failure medications were started or adjusted during the hospital stay. The goal was to see if starting these treatments in the hospital, under close monitoring, could lead to …
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Camera calibration study aims to sharpen prostate cancer imaging
Knowledge-focused CompletedThis study looked at whether a special 3D camera can accurately measure radiation from a prostate cancer drug called lutetium. Researchers used data from 20 patients who had already received the treatment. The goal was to see if images taken at different energy levels give the sa…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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CT scans may help surgeons avoid surprises during Weight-Loss surgery
Knowledge-focused CompletedThis study looked at whether a simple CT scan before weight-loss surgery can help predict when the original surgical plan might need to change during the operation. Researchers reviewed data from 288 adults who had planned gastric bypass surgery, comparing those whose surgery cha…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Ultrasound may spot liver danger before stem cell transplant
Knowledge-focused CompletedThis study looked at whether liver ultrasound and elastography (a special type of ultrasound that measures stiffness) can help predict a serious condition called sinusoidal obstruction syndrome (SOS) before patients receive a stem cell transplant. Researchers followed 114 adult p…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Could your arteries predict memory loss? new study investigates
Knowledge-focused CompletedThis study looks at whether blood vessel health is linked to memory decline in older adults with high blood pressure who have memory complaints. Researchers will measure artery stiffness, brain scans, and cognitive tests in 131 participants over time. The goal is to understand if…
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:20 UTC