MRI may spare babies radiation in kidney blockage diagnosis

NCT ID NCT05498532

Completed Diagnosis Sponsor: Central Hospital, Nancy, France Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether functional MRI can accurately measure kidney function in children with pyelo-ureteral junction syndrome, a common urinary blockage. Researchers compared MRI results to the standard scintigraphy scan in 270 children aged 0-17. The goal was to see if MRI could replace scintigraphy, avoiding radiation exposure, especially in infants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Functional MRI with gadolinium contrast
What this could lead to: If successful, functional MRI could replace scintigraphy for measuring kidney function in young children, avoiding radiation exposure.
What could go wrong: This is a completed observational study, not a treatment trial. MRI may overestimate results and has limited ability to detect certain blood vessels, so it may not fully replace scintigraphy.

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Conditions

The condition(s) this trial relates to.

bilateral multicystic dysplastic kidney congenital anomalies of kidney and urinary tract 2 stricture or kinking of ureter

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STRICTURE OF PELVIURETERIC JUNCTURE

Contacts and locations

Locations

CHRU Nancy

Vandœuvre-lès-Nancy, Lorraine, 54 511, France

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