Central Hospital, Nancy, France

This large study will test whether giving a lower dose of epinephrine (adrenaline) during emergency treatment for cardiac arrest outside hospitals helps more patients survive with good brain function. Over 4,300 adult patients will be randomly assigned to receive either the stand…

This study aims to find a better way to predict how patients with severe alcohol-related hepatitis will fare. Researchers will analyze old liver biopsy samples from 300 people to measure levels of a protein called TREM-1. They want to see if high or low levels of this protein can…

This study is testing a new artificial intelligence (AI) tool designed to improve brain scans used to diagnose Alzheimer's disease. The goal is to see if the AI can maintain scan quality even when using a lower radiation dose or a shorter scan time. This could make the diagnostic…

This study aims to see if a single dose of the antibiotic ceftriaxone works well enough in the body to prevent early pneumonia in critically ill patients with brain injuries who are on breathing machines. It will enroll 60 adults to check if the drug reaches effective levels, esp…

This study looks back at the experiences of women who started the process to donate eggs at a hospital in France. Researchers will review medical records to understand how many donors complete the process, how long it takes, and the outcomes of the donated eggs. The goal is to fi…

This study aims to understand how often mild psychotic symptoms occur in people with epilepsy after they stay in the hospital for specialized brain monitoring. Researchers will follow 110 patients to see if these symptoms happen more frequently than severe episodes and to identif…

This study aims to understand and reduce heart-related risks for patients having surgery to remove adrenal tumors. Researchers will observe over 500 patients across Europe to see how different pre-surgery preparations affect heart complications within 30 days after the operation.…

This study aims to improve MRI scans for Crohn's disease by analyzing tissue removed during surgery. Researchers will perform detailed scans on 60 intestinal specimens to create a precise map of inflammation and scarring. The goal is to validate new scan measurements that could o…

This study aims to create a detailed database of how the body's electrical properties change with age using MRI scans. Researchers will scan 120 healthy volunteers across three age groups (children, adults, and seniors) to gather this information. The goal is to use this data to …

This study aims to understand how different levels of phenylalanine in the blood affect the thinking, emotions, and daily life of adults with PKU. Researchers will observe 30 adults with PKU and a close relative to learn more about their personal experiences. The goal is to gathe…

This study aims to find a connection between how mature the bone in the roof of the mouth is and how developed a person's upper wisdom teeth are. Researchers will look at existing 3D and standard dental X-rays from 200 people to see if the wisdom tooth development, visible on a c…

This study aims to understand if measuring the amount of a specific antibody (anti-Ro52) in the blood can help predict how severe a patient's Sjögren's Syndrome might become. Researchers will follow 150 patients to see if higher antibody levels are linked to more serious organ pr…

This study aims to understand the connection between a parathyroid gland disorder and high blood pressure. Researchers will measure a hormone called aldosterone in 400 patients before and for a year after they have surgery to remove a problematic parathyroid gland. The goal is to…