Central Hospital, Nancy, France

This study looks at whether giving a smaller dose of epinephrine (0.5 mg) during a heart attack outside the hospital can help more people survive with better brain function than the usual dose (1 mg). About 4,300 adults will be randomly assigned to receive either the low or stand…

This study tests whether a deep learning algorithm can clean up brain scan images taken with lower radiation or shorter scan time. 40 people with memory problems will have their existing PET scans processed to simulate lower doses. The goal is to see if the AI-enhanced images are…

This study looks at whether a single dose of the antibiotic ceftriaxone can prevent early pneumonia in patients with serious brain injuries who need a breathing machine. Researchers will check if the drug reaches high enough levels in the blood to kill bacteria, especially in pat…

This study explores whether a hypnosis session is possible and helpful for patients in the intensive care unit (ICU) who are ready to come off a breathing machine (ventilator). The goal is to see if hypnosis can reduce pain and anxiety during this process, potentially making it e…

This study looks at why finger-stick blood tests (capillary) sometimes give different results than standard arm blood draws (venous) for people with antiphospholipid syndrome who take blood thinners. Researchers will compare two finger-stick devices to the usual lab test in 150 a…

This study looks at a protein called TREM-1 in liver cells to see if it can help doctors better diagnose and predict the course of severe alcoholic hepatitis, a life-threatening liver condition. Researchers will compare TREM-1 levels in 300 adults with severe alcoholic hepatitis …

This study aims to find out how often people with drug-resistant focal epilepsy experience mild psychotic symptoms after a seizure, especially during a hospital stay for brain monitoring. Researchers will follow 110 patients and use interviews and questionnaires to track these sy…

This study will observe 522 adults across Europe who are having surgery to remove an adrenal gland tumor. The goal is to see how often serious heart problems happen within 30 days after surgery. Researchers will compare patients with a rare, hormone-releasing tumor (pheochromocyt…

This study looks back at medical records of about 60 people with primary immune deficiencies who also develop lymphoproliferation (abnormal growth of immune cells). Researchers want to track major events like death, cancer, or organ damage over time. The goal is to better underst…

This study looks at how blood phenylalanine (Phe) levels affect thinking, emotions, and daily functioning in 30 adults with PKU. Researchers want to understand why some patients with high Phe levels have no major problems, while others do. The goal is to move toward personalized …

This study looks at intestine tissue removed during surgery from 60 adults with Crohn's disease. Researchers will use special MRI scans and lab tests on the tissue to better understand the difference between active inflammation and permanent scarring. The goal is to improve futur…

This study looks back at the experiences of women who started the egg donation process at Nancy University Hospital after France updated its bioethics laws in 2021. Researchers will review medical records of about 60 donors to see how many completed the donation, how long it took…

This study looks at older adults (70+) admitted to the ICU with a brain bleed from a burst aneurysm. Researchers will review medical records to find factors that predict whether a patient will recover or have a poor outcome at 6 months and 1 year. The goal is to help doctors make…

This study looks at whether measuring a specific antibody, anti-Ro52, in the blood can help predict how Sjögren's syndrome will progress. Researchers will follow 150 adults with Sjögren's to see if higher antibody levels are linked to more severe complications, like organ damage …

This study will use MRI scans to measure the electrical properties of the head, neck, and torso in 120 healthy volunteers split into three age groups: children (6-12), adults (20-40), and seniors (70+). The goal is to create a detailed database that helps make MRI scans safer by …

This study looks at whether the usual dose of an antibiotic (piperacillin) given during major liver or pancreas surgery is enough to prevent infections. Researchers will measure antibiotic levels in 60 adult patients during their operation. The goal is to see if current dosing wo…

This study looks at how a hormone called aldosterone changes in people with primary hyperparathyroidism before and after parathyroid surgery. Researchers will measure aldosterone levels in 400 adults at 3, 6, and 12 months after surgery. They also track blood pressure and medicat…