Could less be more? new trial tests lower epinephrine dose for cardiac arrest
NCT ID NCT07442071
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether giving a smaller dose of epinephrine (0.5 mg) during a heart attack outside the hospital helps more people survive with better brain function than the usual dose (1 mg). About 4,336 adults will be randomly assigned to receive either the low or standard dose. The main goal is to see if the lower dose leads to better neurological outcomes 28 days later.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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AP-HP Hôpital Necker
Paris, France
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Brigade de Sapeurs-Pompiers de Paris
Courbevoie, France
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CH Annecy
Annecy, France
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CH SUD Francilien
Corbeil-Essonnes, France
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CHRU Nancy
Nancy, France
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Besançon, France
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Brest, France
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Colmar, France
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Montpellier, France
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CHU Nice
Nice, France
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Nîmes, France
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Poitiers, France
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Rennes, France
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Rouen, France
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CHU Tours
Tours, France
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Centre Hospitalier Universitaire De Nantes
Nantes, France
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Centre Hospitalier Universitaire De Toulouse
Toulouse, France
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Centre Hospitalier Universitaire Grenoble Alpes
La Tronche, France
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Centre Hospitalier Universitaire Reims
Reims, France
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Centre hospitalier Annecy Genevois Site Julien en GENEVOIS
Saint-Julien-en-Genevois, France
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Centre hospitalier de la Côte Basque
Bayonne, France
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Hopital Beaujon
Paris, France
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Hospices Civils De Lyon
Lyon, France
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La Pitié Salpêtrière
Paris, France
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Raymond Poincaré Hospital
Paris, France
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hôpital Lariboisière
Paris, France
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