Liver protein TREM-1 may predict steroid response in alcoholic hepatitis

NCT ID NCT07176741

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at whether measuring a protein called TREM-1 in liver tissue can help doctors better predict how patients with severe alcoholic hepatitis will do. Researchers will compare TREM-1 levels in 300 people—half with alcoholic hepatitis and half with other liver diseases—using stored biopsy samples. The goal is to see if TREM-1 can guide treatment decisions, like who should get steroids or be considered for a liver transplant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple tissue test that helps doctors predict which patients will respond to steroids and who might need a liver transplant sooner.

What could go wrong

This is an early, observational study using stored tissue samples. It may not prove that TREM-1 is better than existing blood tests, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alcohol abuse alcoholic hepatitis cholangiocarcinoma Fibrosis hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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