Blood cell count may reveal who faces worst outcomes in rare autoimmune disease

NCT ID NCT05989399

Completed Diagnosis Sponsor: Central Hospital, Nancy, France Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examined whether the level of neutrophils, a type of white blood cell, in the blood can help predict how severe antisynthetase syndrome (ASyS) will be. ASyS is a rare autoimmune disease that can cause muscle inflammation, lung disease, and other symptoms. Researchers looked at data from 89 patients to see if a high neutrophil count at diagnosis was linked to more severe disease. The goal is to find a simple, widely available test to identify high-risk patients early.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple blood test to identify which patients with antisynthetase syndrome are at risk for severe disease, helping doctors intervene earlier.
What could go wrong: This is a small, retrospective study that only looks back at existing data. The findings may not apply to all patients and need to be confirmed in larger, prospective trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

antisynthetase syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTISYNTHETASE SYNDROME

Contacts and locations

Locations

CHU Nancy

Nancy, France

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