Engineered immune cells take aim at stubborn autoimmune diseases

NCT ID NCT07490951

First seen Apr 05, 2026 · Last updated Apr 25, 2026 · Updated 3 times

Summary

This early study will test a new treatment called CD19/BCMA CAR-T in 20 adults with severe autoimmune diseases like lupus or Sjögren's syndrome that haven't improved with standard therapies. The treatment uses a patient's own immune cells, modified in a lab to target and attack faulty immune cells driving the disease. The main goals are to check safety and find a safe dose, with initial signs of effectiveness also being monitored.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AUTOIMMUNE DISEASES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Wuhan No.1 Hospital

    Wuhan, Hubei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.