Baylor Research Institute

This study tests a healthy lifestyle program designed for people who have had a stroke. The program focuses on weight loss and increasing physical activity. Researchers will track 65 participants for 12 months to see if the program helps them achieve lasting health improvements.

This study compares two ways of giving the blood thinner heparin to adults on a heart-lung machine (ECMO) for severe breathing problems. One group gets the standard IV drip, the other gets a shot under the skin. Researchers will check for bleeding, dangerous clots, and survival. …

This study looks at whether a drug called everolimus can help prevent liver cancer from returning in people who have had a liver transplant for a type of liver cancer that is harder to treat. About 336 adults who are at high risk for their cancer coming back will be randomly assi…

This study planned to test whether curcumin, a natural compound found in turmeric, could safely help shrink or eliminate high-grade cervical precancerous lesions (CIN3) in women. It aimed to enroll women aged 21 and older with confirmed CIN3 and give them oral curcumin for 12 wee…

This study tests a combination of two drugs, abemaciclib and ramucirumab, in people with advanced esophageal or gastroesophageal junction cancer that has spread. The goal is to see if the combination is safe and can help control tumor growth. About 8 participants will receive the…

This study tests a weight-loss program designed for people with traumatic brain injury (TBI). The program, called Group Lifestyle Balance, focuses on healthy eating and physical activity. Researchers will track weight, step count, and other health measures over 18 months in 57 ad…

This study tests a weight-loss program delivered by video for people with traumatic brain injury (TBI). The program is based on the Diabetes Prevention Program and is adapted for TBI. About 85 adults with moderate to severe TBI and a BMI of 25 or higher will take part. The goal i…

This study tests a new approach called targeted plasticity therapy for people with spinal cord injuries who have arm weakness. It uses mild electrical pulses on the vagus nerve in the neck during rehab exercises to help the brain and spinal cord rewire. Twenty adults aged 18-64 w…

This study aimed to see if using cold saline to inflate a balloon inside the uterus could reduce blood loss after childbirth better than room temperature saline. It was designed for women 18-45 who had just delivered vaginally and had uncontrolled bleeding. However, the study was…

This study tests if a uterus transplant from a living or deceased donor can help women born without a uterus or who had it removed to have a baby. About 38 women with working ovaries will get a transplant and then try IVF. The main goal is a successful live birth, but women will …

This study aimed to see if taking antibiotics for 3 days after prostate surgery (HoLEP) lowers the chance of a urinary tract infection. It was planned for men over 40 with an enlarged prostate and no current infection. However, the study was withdrawn before enrolling anyone, so …

This study planned to give hospitalized adults with COVID-19 pneumonia plasma from people who had recovered from the virus. The goal was to see if this plasma could reduce the need for oxygen or breathing support. However, the trial was withdrawn before enrolling any participants…

This study tests whether a workshop led by fellow firefighters can help prevent PTSD, depression, anxiety, and alcohol problems in new firefighter trainees. About 480 recruits will take part during their academy training. They will either receive the emotion-regulation workshop o…

This study tests if a new non-opioid painkiller (suzetrigine) works as well as a standard opioid for pain after Mohs skin cancer surgery. About 75 adults having Mohs surgery will receive either suzetrigine or hydrocodone/acetaminophen. The goal is to see if the non-opioid option …

This study compares two numbing medications—BDE and Exparel—to see which one helps hernia surgery patients feel less pain and use fewer painkillers. About 128 adults having abdominal wall reconstruction will take part. The goal is to find the best way to manage pain, shorten hosp…

This study tests a brief form of therapy called Brief Prolonged Exposure (Brief PE) to see if it can reduce posttraumatic stress in people who have had a spinal cord injury. About 200 adults in inpatient rehab will either get this therapy or standard care. The goal is to ease PTS…

This study aimed to see if a laparoscopic-guided nerve block (TAP block) could reduce the need for strong painkillers after weight-loss or stomach surgery. It planned to compare two numbing medicines, but the study was withdrawn before enrolling any participants. No results are a…

This study tests whether an Enhanced Recovery After Surgery (ERAS) protocol can lower the need for strong painkillers after a live donor kidney transplant. About 60 adult patients will follow a special plan that includes a pre-surgery drink, Tylenol, gabapentin, a numbing injecti…

This study tests a new wireless device that uses mild nerve stimulation during physical therapy to help people who had a stroke at least a year ago. The goal is to see if it is safe and can improve arm and hand movement. About 42 adults aged 22 to 79 with moderate arm weakness wi…

This study aimed to find the best way to give tube feedings to head and neck cancer patients receiving chemoradiation. It compared three methods: bolus, gravity drip, and pump. The goal was to see which method helped patients maintain weight and tolerate feedings best. However, t…

This study looks at whether corticosteroids can improve swallowing in people with EGJOO, a condition where the esophagus doesn't relax properly, causing food to get stuck and chest pain. Researchers think an allergy might be the cause. Twelve adults with confirmed EGJOO will take…

This study tests whether shining a special near infrared light on the head can boost brain cell activity and repair in people with early to mid-stage dementia. Researchers will measure memory, thinking, and brain wave changes over 8 weeks in 100 participants aged 50-85. The goal …

This study planned to compare a tiny steroid insert (Dextenza) with standard steroid eye drops for controlling inflammation after cataract surgery in people with diabetes. It aimed to see which worked better at preventing swelling and fluid buildup in the eye. However, the study …

This study aims to improve mental health care access for minority communities by training students from underrepresented backgrounds to become certified community health workers (CHWs). About 1500 students will receive training and internship opportunities to address mental healt…

This study looks at how common anesthetics change the way the esophagus moves during a special imaging test called FLIP. Researchers will study 30 adults with swallowing problems like achalasia. The goal is to better understand these effects to improve future treatments.

This study is testing a new exercise test called CASE to help athletes aged 10-22 safely return to sports after a concussion. The test mimics movements from sports like soccer and basketball to see how the body responds to exertion. Researchers will measure heart rate, blood pres…

This study interviews 15 adults aged 30-70 to learn why some people do not join cancer research studies. The goal is to make future studies more inclusive and effective for everyone in the U.S. No treatments or tests are involved—only conversations to gather insights.

This study will check if a wellness program at Bonton Farms helps people in the Bonton neighborhood improve their heart health and quality of life. About 300 adults will take part for 12 months, and researchers will track things like diet, exercise, sleep, and blood pressure. The…