Could a drug combo stop liver cancer from coming back after transplant?

NCT ID NCT02081755

First seen Jan 29, 2026 · Last updated May 16, 2026 · Updated 18 times

Summary

This study looks at whether a drug called everolimus can help prevent liver cancer from returning in people who have had a liver transplant for a type of liver cancer that is harder to treat. About 336 adults who are at high risk for their cancer coming back will be randomly assigned to receive either everolimus plus another drug or a standard drug combination. The main goal is to see which group lives longer without the cancer returning or dying.

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Contacts and locations

Locations

  • Baylor University Medical Center

    Dallas, Texas, 75246, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Mount Sinai Medical Center

    New York, New York, 10029, United States

  • Northwestern University School of Medicine

    Chicago, Illinois, 60611, United States

  • University of California at San Francisco

    San Francisco, California, 94143, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Tennessee- Methodist University Hospital

    Memphis, Tennessee, 38104, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.