Baylor College Of Medicine

This early-phase study tests a new treatment for advanced osteosarcoma and neuroblastoma that has not responded to standard therapies. The approach uses a patient's own immune cells (T cells) that are genetically modified to recognize and attack cancer cells carrying a protein ca…

This early-phase study tests a new gene therapy for children with neuroblastoma that has come back or not responded to treatment. The therapy uses the patient's own immune cells (T cells) that are modified in the lab to recognize and attack neuroblastoma cells. The study aims to …

This early-phase study tests a new treatment for people with B-cell lymphoma or leukemia that has returned or not responded to standard therapy. The treatment uses the patient's own T cells, which are modified in the lab to recognize and attack cancer cells carrying a protein cal…

This early-phase study tests a new therapy using specially trained immune cells from a donor to target and kill cancer cells in people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) whose disease has returned or not gone away after a stem cell transplant. The…

This early-stage study tests a new treatment for adults with acute myeloid leukemia (AML) that has returned or not responded to standard therapy. The treatment uses the patient's own immune cells, called T cells, which are modified in a lab to recognize and attack AML cells carry…

This early-phase study tests a new treatment for people with relapsed lymphoma tied to the Epstein-Barr virus. The therapy uses the patient's own immune cells, modified to resist a substance tumors use to hide. The goal is to find a safe dose and see if these cells can shrink tum…

This study tests a new treatment called AGAR T cells for children whose solid tumors (like liver cancer or Wilms tumor) have returned or not responded to standard care. The treatment involves taking a patient's own immune cells, adding genes to help them recognize and attack tumo…

This study tests a video-based program called VITAL Start for Adolescents to help teens living with HIV take their medication regularly and stay healthy. About 1,800 teens and their caregivers in Malawi will either watch the videos plus get standard care, or just get standard car…

This early-phase study tests a new approach for people with CD19-positive blood cancers (like lymphoma or leukemia) that returned after a stem cell transplant. Researchers take immune cells (T cells) from the original stem cell donor, modify them to better recognize and attack ca…

This study tests a new treatment for people with advanced sarcoma, a type of cancer that has not responded to standard therapies. Researchers take a patient's own immune cells (T cells) and add a new gene to help them recognize and attack cancer cells that have a protein called H…

This study looks at whether a weight loss program called "Paso a Paso" is practical for Mexican and Central American adults with fatty liver disease and overweight. Researchers will track attendance, weight loss, liver health, and diet changes in 50 participants. The goal is to s…

This study tests whether a non-invasive headband device, originally approved for migraines, can help reduce seizures in veterans with drug-resistant epilepsy. 24 veterans will receive either standard care alone or standard care plus the device, then switch groups. The goal is to …

This study tests a new ultrasound otoscope to better diagnose middle ear infections in children. About 300 kids scheduled for ear tube surgery will have their ears scanned with the device. The goal is to see if the ultrasound can tell the difference between infected and non-infec…

This study compares a new bipolar knife to a standard monopolar knife for removing colon growths through a scope. About 80 adults will take part to see which knife works faster and causes fewer side effects like bleeding or pain. The goal is to improve the surgery experience and …

This study planned to see if adding ear acupuncture during surgery to repair a broken lower leg could lower the amount of opioid painkillers patients needed afterward. It was designed for adults aged 18 to 64 having ankle surgery. However, the study was withdrawn before any parti…

This study planned to test whether giving patients ear acupuncture during wrist fracture surgery would lower their need for opioid painkillers afterward. It was designed for adults aged 18-64 having a specific type of wrist repair. However, the study was withdrawn before any part…

This study looks at whether giving supplements that boost glutathione—a natural antioxidant in the body—can improve memory and thinking in older adults with mild cognitive impairment. Sixty participants will take either the active supplements or a placebo for 12 weeks, then stop …

This study looks at how well noninvasive tests (like blood markers and special scans) can detect liver scarring in people with urea cycle disorders. About 62 participants aged 6 to 65 will be tested at five medical centers. The goal is to find better ways to monitor liver health …

This study is for people with severe, hard-to-treat OCD. Researchers are testing an advanced brain stimulation system that can adapt to brain signals. The goal is to find reliable brain markers of OCD distress, which could lead to better treatments in the future. Only 2 participa…

This study tests whether a series of short educational videos can help parents of teens with anorexia feel more knowledgeable, confident, and less stressed. About 50 families will either receive standard care or standard care plus the videos. Researchers will check if parents fin…

This study aims to better understand the genetic causes of Goltz syndrome, a rare condition that affects the skin, skeleton, eyes, and other organs. Researchers collect blood samples from up to 84 participants and their parents to analyze DNA and identify mutations. The goal is t…

This study follows up on very low birth weight babies (under 1000 grams) who received either a standard or high-protein diet while in the NICU. Researchers want to see if the high-protein diet leads to better growth, body composition, and brain development when the children are 1…