Engineered immune cells take aim at blood cancers in early trial

NCT ID NCT00586391

First seen Feb 06, 2026 · Last updated May 17, 2026 · Updated 15 times

Summary

This early-phase study tests a new treatment for people with B-cell lymphoma or leukemia that has returned or not responded to standard therapy. The treatment uses the patient's own T cells, which are modified in the lab to recognize and attack cancer cells carrying a protein called CD19. The main goals are to find a safe dose and to see if these engineered cells can shrink tumors.

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Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.