Assistance Publique Hopitaux De Marseille

This study tests a non-invasive brain training technique called neurofeedback for people with drug-resistant epilepsy. Participants learn to change their own brain activity to reduce seizures. The study compares real neurofeedback to a sham (fake) version to see if it truly works…

This study looks at whether a specific antibody in the blood (anti-CD146) can help doctors diagnose lung diseases caused by breathing in silica dust at work. Silica exposure can lead to serious lung problems like scarring and cancer, but there is no easy test to catch it early. R…

This study tests whether a near-infrared light device can accurately measure fat in the liver without needing a biopsy. Researchers will use the device on 90 donated livers and surgical samples to see if it can detect dangerous fat levels quickly and painlessly. If successful, it…

This study aims to develop an artificial intelligence system that can analyze 3D whole-body skin scans to help doctors detect melanoma, a serious type of skin cancer. Researchers will collect images from 1,000 adults who have many moles and compare the AI's findings with those of…

This study tests a new way to prevent sexual violence in women seeking asylum in France. Researchers will compare a coordinated care model that combines medical, psychological, social, and legal support with standard care. 675 women who recently applied for asylum will take part,…

This study compares a joint consultation with a lung doctor (pulmonologist) and an ear-nose-throat (ENT) specialist against separate visits for adults with asthma and chronic sinusitis with nasal polyps. The main goal is to see if the combined approach reduces the need for oral s…

This study tests a slow-release melatonin (PedPRM) in 120 children aged 6 to 18 who have anorexia nervosa and trouble sleeping. Participants take either melatonin or a placebo for 13 weeks. The goal is to see if it safely improves total sleep time and related symptoms like anxiet…

This study tests whether a spinal cord stimulator can reduce chronic nerve pain caused by chemotherapy. About 68 adults with pain lasting over a year will get the device implanted and then try both active and sham stimulation to see which works better. The goal is to find a new o…

This study looks at tiny organisms in the mouth that may cause health problems in older adults (60+) and people with weakened immune systems. Researchers will collect dental plaque and saliva samples from 250 participants to see how common these imbalances are. The goal is to fin…

This study looks at why a heat-based brain treatment (SEEG-guided thermocoagulation) helps some people with hard-to-control epilepsy but not others. Researchers will use brain scans and blood tests to find markers that predict success. The goal is to better select patients who wi…

This study looks at 50 adults with primary central nervous system lymphoma who are receiving high-dose methotrexate, a key chemotherapy. The goal is to see if measuring the drug early in the blood can predict later kidney problems. By identifying at-risk patients sooner, doctors …

This study aims to understand why some people with chronic lung disease develop pulmonary hypertension (high blood pressure in the lungs). Researchers will compare lung tissue from 105 adults undergoing lung surgery, including those with and without pulmonary hypertension. By exa…

This study looks at whether teenagers with severe scoliosis have trouble sensing where their body is in space (proprioception). Researchers will compare brain scans and muscle measurements of 60 teens with scoliosis to healthy controls. The goal is to understand if these issues a…

This study will follow 100 adults who need a stoma (an opening in the belly to pass waste). It compares those who get education and stoma site marking before surgery to those who do not. The goal is to see if this preparation improves quality of life and reduces early problems li…

This study looks at how Gamma Knife radiosurgery affects brain connections in people with severe facial pain called trigeminal neuralgia. About 28 adults will get brain scans before treatment and at 1, 3, and 12 months after. The goal is to understand how the treatment works in t…

This study checks if physiotherapists get chemotherapy drugs inside their bodies after treating patients who recently received these drugs. Twenty physiotherapists will provide urine and skin samples before and after giving massages or other hands-on care. The goal is to understa…

This study aims to develop a simple blood test that checks how well a person's immune cells can fight blood cancer. Researchers will collect blood samples from 166 adults with blood cancers to measure immune cell activity and look at genetic factors. The goal is to create a test …

This study aims to create and test improved MRI techniques for people with multiple sclerosis (MS). Researchers will scan 272 healthy volunteers and MS patients using high-field (3T) and ultra-high-field (7T) MRI machines. The goal is to standardize these scans, establish normal …

This study follows 75 young adults with severe hemophilia who were part of an earlier study as teens. Researchers want to see if their healthcare habits change as they become adults and what factors help them stick to treatment. The goal is to understand how to support a smooth t…

This study looks for ways to predict which cancer patients will have severe side effects from immunotherapy drugs. Researchers will analyze blood, gut bacteria, and other routine tests from 160 adults with solid tumors before and during treatment. The goal is to create a risk pro…