New blood test may spot silica lung damage before symptoms appear
NCT ID NCT07376291
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a specific antibody in the blood, called anti-CD146, can help doctors diagnose lung diseases caused by breathing in silica dust at work. Silica exposure can lead to serious lung problems like scarring, inflammation, and cancer, but there is currently no simple blood test to catch these diseases early. Researchers will compare 110 people with and without silica exposure to see if the antibody levels differ and relate to lung health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Anti-CD146 autoantibodies (AACD146) as a blood biomarker
What this could lead to
If successful, this could lead to a simple blood test for early detection of silica-related lung diseases, allowing earlier treatment.
What could go wrong
This is an early-stage diagnostic study, not a treatment trial. The biomarker may not prove accurate enough for clinical use, and results may not apply to all exposed workers.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for EXPOSURE OCCUPATIONAL are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.