RHABDOMYOSARCOMA

This study is testing a new drug called CLR 131 in children and young adults whose cancers have come back or haven't responded to standard treatments. The drug is designed to deliver radiation directly to cancer cells. The main goals are to find a safe dose and see if the drug sh…

This study is testing a more precise form of radiation therapy for children and young adults with bone and soft tissue cancers like sarcoma. The goal is to see if using advanced imaging to guide the radiation can better control the tumor while causing fewer long-term side effects…

This early-phase study is testing a new type of cell therapy called AGAR T cells in children and young adults with solid tumors that have come back or haven't responded to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to better recognize and…

This study is for children and young adults (up to age 40) with intermediate-risk rhabdomyosarcoma, a type of muscle cancer. It compares the current standard chemotherapy to the same chemotherapy plus a newer drug called temsirolimus. The goal is to see if adding temsirolimus hel…

This study is testing a new combination of two drugs, cobolimab and dostarlimab, for children and young adults with advanced solid tumors that have not responded to other treatments. The main goals are to find the safest and most effective dose and to see how well the body tolera…

This study is testing a personalized treatment plan for children and young adults with rhabdomyosarcoma, a rare muscle cancer. Doctors use proton beam radiation, surgery, and chemotherapy tailored to each patient's risk level. The goal is to control the cancer while reducing side…

This study is testing four different ways to time chemotherapy for a rare and aggressive type of childhood muscle cancer that has spread. The goal is to see if changing when and how chemotherapy is given can better control the cancer and prevent it from coming back. Patients and …

This study is testing whether a pill called cabozantinib can help control rare cancers that have come back or stopped responding to other treatments in children and young adults. It includes patients with sarcomas, Wilms tumor, and other rare tumors. The drug aims to slow or stop…

This study is testing whether a new drug called PEN-866, when combined with two standard chemotherapy drugs (vincristine and temozolomide), can help control aggressive cancers that have returned or not responded to other treatments. It is for adolescents and young adults (ages 12…

This early-stage study is testing a new type of personalized cell therapy for children and young adults whose solid tumors have come back or haven't responded to other treatments. Doctors take a patient's own immune cells, modify them in a lab to better recognize and attack cance…

This early-stage study is testing a new type of treatment called CATCH T cells in adults with advanced solid tumors that have a specific marker (GPC3). Doctors take a patient's own immune cells, genetically modify them in a lab to better recognize and attack cancer, and then infu…

This early-phase study is testing the safety and feasibility of a new treatment called CAR T-cell therapy for children and young adults whose solid tumors have come back or not responded to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to be…

This study is testing a new type of imaging scan to see if it can better detect and monitor tumors in children and young adults with cancer. The scan uses a radioactive form of a natural protein building block called methionine. Researchers want to see how well this new scan work…