RHABDOMYOSARCOMA
Clinical trials for RHABDOMYOSARCOMA explained in plain language.
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New drug cocktail shows promise for rare sarcomas
Disease control CompletedThis study tested a combination of two drugs, cobimetinib and atezolizumab, in children and adults with advanced soft tissue sarcoma that has spread. The goal was to see if the combo is safe and can stop tumors from growing. About 229 people took part, and researchers measured ho…
Matched conditions: RHABDOMYOSARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Centre Leon Berard • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Promising drug cocktail targets tough sarcomas in young patients
Disease control CompletedThis study tested a combination of two chemotherapy drugs, nab-paclitaxel and gemcitabine, in 59 teenagers and young adults whose sarcoma (a type of bone or soft tissue cancer) had returned or not responded to standard treatment. The main goals were to see if the drug combo could…
Matched conditions: RHABDOMYOSARCOMA
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New stem cell transplant shows promise for kids with tough cancers
Disease control CompletedThis study tested a new way to do stem cell transplants in 23 children with cancers that came back or didn't respond to treatment. The method removes certain immune cells from the donor's stem cells to help the child's body recover faster and fight infections better. The goal was…
Matched conditions: RHABDOMYOSARCOMA
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Experimental drug cocktail targets tough childhood cancers in adults
Disease control CompletedThis study tested a combination of two drugs, olaparib and temozolomide (with or without irinotecan), in 49 adults with Ewing sarcoma or rhabdomyosarcoma that had come back or spread after standard chemotherapy. The main goal was to find the safest dose and see if the combo could…
Matched conditions: RHABDOMYOSARCOMA
Phase: PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New hope for young cancer patients: drug shows promise against tough tumors
Disease control CompletedThis study tested the drug lenvatinib in 127 children, adolescents, and young adults whose solid tumors had come back or stopped responding to treatment. The goal was to see if the drug could shrink tumors and to check for side effects. Participants received lenvatinib daily, and…
Matched conditions: RHABDOMYOSARCOMA
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Could a Radiation-Free MRI replace risky scans for kids with cancer?
Knowledge-focused CompletedThis study tested whether a special MRI technique called diffusion-weighted MRI (DWI-MRI) can safely and accurately stage sarcomas in children without using radiation. 98 children with bone or soft-tissue sarcomas received DWI-MRI scans, and researchers compared the results to st…
Matched conditions: RHABDOMYOSARCOMA
Phase: NA • Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Can a simple spit test predict chemo-related deafness in kids?
Knowledge-focused CompletedThis study looked at 119 children who had platinum-based chemotherapy for certain cancers. Researchers wanted to find out if certain genes make some kids more likely to develop hearing loss from the treatment. By analyzing DNA from saliva samples, they hope to identify high-risk …
Matched conditions: RHABDOMYOSARCOMA
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Can a Child's tumor DNA guide better cancer treatment?
Knowledge-focused CompletedThis study tested whether analyzing the DNA and RNA of a child's tumor could help doctors choose personalized treatments. It included 186 children with relapsed or hard-to-treat cancers like neuroblastoma and brain tumors. The goal was to see if this approach was feasible and saf…
Matched conditions: RHABDOMYOSARCOMA
Phase: NA • Sponsor: Giselle Sholler • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC