New chemo timing strategies aim to outsmart aggressive childhood cancer
NCT ID NCT04388839
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests four different chemotherapy schedules in children and adults with a rare, aggressive muscle cancer that has spread. Participants choose from a first-strike approach, a first-strike followed by maintenance, an adaptive schedule, or standard chemo. The goal is to see which timing works best to delay cancer return and improve survival.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Carolinas Medical Center, Levine Cancer Institute
Charlotte, North Carolina, 28204, United States
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Children's Hospital of Colorado
Aurora, Colorado, 80045, United States
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Cleveland Clinic
Cleveland, Ohio, 44106, United States
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Connecticut Children's Medical Center
Hartford, Connecticut, 06106, United States
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Duke Children's Hospital
Durham, North Carolina, 27710, United States
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Johns Hopkins All Children's Hospital
St. Petersburg, Florida, 33701, United States
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MD Anderson
Houston, Texas, 77030, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Montefiore Medical Cancer Center
The Bronx, New York, 10467, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Primary Children's Medical Center/Utah
Salt Lake City, Utah, 84113, United States
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Roswell Park Comprehensive Cancer Center
Buffalo, New York, 14263, United States
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University of Alabama at Birmingham Comprehensive Cancer Center
Birmingham, Alabama, 35294, United States
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University of Florida
Gainesville, Florida, 32610, United States
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University of Miami - Sylvester Comprehensive Cancer Center
Miami, Florida, 33136, United States
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University of North Carolina Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
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Vanderbilt - Ingram Cancer Center
Nashville, Tennessee, 37232, United States